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Volume 24, Number 2—February 2018

Development of a Pediatric Ebola Predictive Score, Sierra Leone1

Felicity Fitzgerald2Comments to Author , Kevin Wing2, Asad Naveed, Musa Gbessay, J.C.G. Ross, Francesco Checchi, Daniel Youkee, Mohamed Boie Jalloh, David E. Baion, Ayeshatu Mustapha, Hawanatu Jah, Sandra Lako, Shefali Oza, Sabah Boufkhed, Reynold Feury, Julia Bielicki, Elizabeth Williamson, Diana M. Gibb, Nigel Klein, Foday Sahr, and Shunmay Yeung
Author affiliations: University College London Great Ormond Street Institute of Child Health, London, UK (F. Fitzgerald, N. Klein); Save the Children, Freetown, Sierra Leone, and London (F. Fitzgerald, K. Wing, A. Naveed, M. Gbessay, J.C.G. Ross, F. Checchi); London School of Hygiene & Tropical Medicine, London (K. Wing, F. Checchi, S. Oza, S. Boufkhed, E. Williamson, S. Yeung); Kings Sierra Leone Partnership, Kings Centre for Global Health, Kings College London, London (D. Youkee); 34 Military Hospital, Republic of Sierra Leone Armed Forces, Freetown (M.B. Jalloh, F. Sahr); Ola During Children’s Hospital, Sierra Leone Ministry of Health, Freetown (D.E. Baion, A. Mustapha); Cap Anamur (German Emergency Doctors), Ola During Children’s Hospital, Freetown (H. Jah); Welbodi Partnership, Ola During Children’s Hospital, Freetown (S. Lako); Western Area Emergency Response Centre, Freetown (R. Feury); MRC Clinical Trials Unit at UCL, London (J. Bielicki, D.M. Gibb); Farr Institute of Health Informatics, London (E. Williamson)

Main Article

Table 2

Scores for each of the variables included in Ebola pediatric predictive model

Variable Coefficient (95% CI) from multivariable model p value Integer score value
Positive contact 2.21 (1.58–2.83) <0.001 +2
Conjunctivitis 1.34 (0.62–2.05) <0.001 +2
Age >2 y 1.06 (0.37–1.75) 0.003 +2
Fever 0.99 (–0.66 to 2.63) 0.241 +1
Anorexia 0.59 (–0.18 to 1.35) 0.133 +1
Male gender 0.49 (–0.11 to 1.08) 0.111 +1
Abdominal pain 0.42 (–0.23 to 1.08) 0.205 +1
Diarrhea 0.40 (–0.21 to 1.01) 0.197 +1
Difficulty breathing –0.57 (–1.39 to 0.24) 0.168 −1
Difficulty swallowing –0.59 (–1.39 to 0.19) 0.138 −1
Headache –0.63 (–1.29 to 0.35) 0.063 −1
Rash 1.00 (–2.13 to 0.14) 0.085 −2

Main Article

1Preliminary results from this study were presented at the 26th European Congress of Clinical Microbiology and Infectious Diseases, Amsterdam, Netherlands, April 9–12, 2016; and the 34th Annual Meeting of the European Society for Pediatric Infectious Diseases, Brighton, UK, May 10–14, 2016.

2These authors contributed equally to this article.

Page created: January 17, 2018
Page updated: January 17, 2018
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