Volume 24, Number 8—August 2018
Susceptibility of Human Prion Protein to Conversion by Chronic Wasting Disease Prions
||Specimen ID||Disease in captive animals or experimental transmission||Prnp genotype, known relevant polymorphisms|
||North American or Rocky Mountain elk or wapiti
||Closely related to red deer (Cervus elaphus)
||Elk 0†||Captive||132 MM|
|Elk 1||Captive||132 MM|
|Elk 2||Captive||132 MM|
|Elk 3||Captive||132 MM|
|Elk 4||Captive||132 MM|
|Elk 5||Captive||132 ML|
||Related to roe deer (Capreolus capreolus)
||WTD 1||Experimental||96 GG|
|Rangifer tarandus subspecies||Caribou (free-ranging) or reindeer (captive)||Reindeer (free-ranging and captive)||Reindeer 1||Experimental (transmission of WTD [CWD 96GG])‡||§|
|Reindeer 2||Experimental [transmission of WTD (CWD 96GG)]¶||§|
*CWD, chronic wasting disease; WTD, white-tailed deer.
†Previously reported in Barria et al. (15).
‡Case 12 previously reported in Mitchell et al. (19).
§Reportedly identical to the case of CWD in a wild reindeer in Norway (Benestad et al. ).
¶Case 47 previously reported in Mitchell et al. (19).