Volume 25, Number 10—October 2019
Research
Sensitive and Specific Detection of Low-Level Antibody Responses in Mild Middle East Respiratory Syndrome Coronavirus Infections
Figure 4
![Reactivity to Middle East respiratory syndrome coronavirus of serum samples from 2 patients with human coronavirus OC43 in different assays. Longitudinal serum samples, collected before and after OC43 infection, from the 2 patients (red, patient 1; black, patient 2) were analyzed by commercial IgG S1 ELISA (A); in-house IgG S1 ELISA (B); S1 protein microarray(C); and PRNT90 (D). Dotted line indicates the cutoff for each assay. Error bars indicate 95% CIs. OD, optical density; PRNT90, 90% reducti](/eid/images/19-0051-F4.jpg)
Figure 4. Reactivity to Middle East respiratory syndrome coronavirus of serum samples from 2 patients with human coronavirus OC43 in different assays. Longitudinal serum samples, collected before and after OC43 infection, from the 2 patients (red, patient 1; black, patient 2) were analyzed by commercial IgG S1 ELISA (A); in-house IgG S1 ELISA (B); S1 protein microarray(C); and PRNT90 (D). Dotted line indicates the cutoff for each assay. Error bars indicate 95% CIs. OD, optical density; PRNT90, 90% reduction in plaque reduction neutralization test; RFU, relative fluorescence units.
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