Volume 25, Number 2—February 2019
Synopsis
Trends of Human Plague, Madagascar, 1998–2016
Table 1
Sensitivity and specificity of microscopy and F1RDT for the diagnosis of human plague cases, Madagascar*
Clinical form | Microscopy, 1998–2001 |
F1RDT, 2002–2008 |
|||
---|---|---|---|---|---|
Sensitivity | Specificity | Sensitivity | Specificity | ||
Bubonic | 34% (31%–38%) | 96% (95%–97%) | 100% (99%–100%) | 60% (58%–62%) | |
Pneumonic |
53% (34%–71%) |
94% (84%–98%) |
100% (90%–100%) |
45% (37%–52%) |
|
Total | 35% (32%–39%) | 96% (95%–97%) | 100% (99%–100%) | 59% (57%–61%) |
*Values in parentheses are ranges. Bacteriological culture was used as a reference test. F1RDT, Yersinia pestis antigen fraction 1 rapid diagnostic test.
1These authors contributed equally to this article.
2Current affiliation: Institut Pasteur, Phnom Penh, Cambodia.
3Retired.
4Current affiliation: Centers for Disease Control and Prevention, Atlanta, Georgia, USA.