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Volume 25, Number 4—April 2019
Research

Sand Fly–Associated Phlebovirus with Evidence of Neutralizing Antibodies in Humans, Kenya

David P. TchouassiComments to Author , Marco Marklewitz, Edith Chepkorir, Florian Zirkel1, Sheila B. Agha, Caroline C. Tigoi, Edith Koskei, Christian Drosten, Christian Borgemeister, Baldwyn Torto, Sandra Junglen2Comments to Author , and Rosemary Sang2
Author affiliations: International Centre of Insect Physiology and Ecology, Nairobi, Kenya (D.P. Tchouassi, E. Chepkorir, S.B. Agha, C.C. Tigoi, B. Torto, R. Sang); Charité-Universitätsmedizin Berlin, Berlin, Germany (M. Marklewitz, F. Zirkel, C. Drosten, S. Junglen); German Center for Infection Research, Berlin (M. Marklewitz, F. Zirkel, C. Drosten, S. Junglen); Center for Virus Research, Kenya Medical Research Institute, Nairobi (E. Koskei, R. Sang); University of Bonn, Bonn, Germany (C. Borgemeister)

Main Article

Table

NT reactivity with NPV, GFV, KARV, and RVFV of serum samples from febrile persons and healthy controls in Kenya*

Sample ID Origin Age, y/sex Occupation Acute febrile infection† Reactivity against
NPV RVFV GBV KARV
H01 Marigat 8/F Student Fever/chills, head/joint/muscle aches 1:40 None None None
H02 Marigat 10/F Student Fever/chills, cough, head/joint/muscle aches, eye pain, diarrhea 1:20 None None None
H03 Marigat 18/F Student Fever/chills, cough, head/joint/muscle aches, jaundice, abdominal pain 1:40 None None None
H04 Marigat 19/M Shop attendant Acute febrile illness—fever/chills, cough, head/muscle aches 1:20 None None None
H05 Marigat 29/M Driver Fever/chills, head/joint/muscle aches 1:80 None None None
H06 Sangailu 17/F Housewife Fever 1:40 None None None
H07 Sangailu 25/M Herdsman Fever/chills, headache, diarrhea 1:320 1:1,280 None None
H08 Sangailu 42/F Housewife Fever/chills, headache, abdominal pain 1:40 None None None
H09 Sangailu 50/F Housewife Fever/chills, cough, head/joint/muscle aches 1:20 None None None
H10 Sangailu 24/M Herder Fever/chills, head/joint/muscle aches, diarrhea 1:320 None None None
H11 Sangailu 53/F Housewife Fever, cough, headache, abdominal pain, muscle ache 1:20 None None None
H12 Sangailu 26/M Shepherd Healthy control 1:20 None None None
H13 Sangailu 30/F Housewife Healthy control 1:160 None None None
H14 Sangailu 65/M Pastoralist Healthy control 1:40 1:320 None None
H15 Sangailu 62/M Herdsman Healthy control 1:80 1:640 None None
H16 Sangailu 34/F Housewife Healthy control 1:80 None None None
H17 Sangailu 52/F Housewife Healthy control 1:20 None None None
H18 Sangailu 50/M Herdsman Healthy control None 1:1,280 None None
H19 Sangailu 57/M Herdsman Healthy control None 1:320 None None
H20 Sangailu 16/M Herder Fever/chills, head/joint/muscle aches, abdominal pain 1:160 1:160 None None
H21 Sangailu 18/M Student Fever, cough, headache, abdominal pains 1:80 None None None
H22 Sangailu 9/F Student Fever/chills, cough, abdominal pains, joint/muscle aches 1:160 None None None
H23 Sangailu 19/F Housewife Fever/chills, headache, abdominal pains 1:40 None None None
H24 Sangailu 30/F Housewife Fever, head/joint/muscle aches, abdominal pain 1:160 1:40 None None
H25 Sangailu 17/M Herder Fever/chills, head/joint/muscle aches, abdominal pain 1:160 None None None
H26 Marigat 17/M Student Fever/chills, head/joint/muscle aches 1:40 None None None

*GFV, Gabek Forest virus; ID, identification; KARV, Karimabad virus; NPV, Ntepes virus; NT, neutralizing test; RVFV, Rift Valley fever virus.
†Fever defined as body temperature >38°C.

Main Article

1Current affiliation: Biotest AG, Dreieich, Germany.

2These authors contributed equally to this article.

Page created: March 17, 2019
Page updated: March 17, 2019
Page reviewed: March 17, 2019
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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