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Volume 25, Number 6—June 2019

Performance of 2 Commercial Serologic Tests for Diagnosing Zika Virus Infection

Séverine Matheus, Cheikh Talla, Bhety Labeau, Franck de Laval, Sébastien Briolant, Lena Berthelot, Muriel Vray, and Dominique RoussetComments to Author 
Author affiliations: Institut Pasteur de la Guyane, Cayenne, French Guiana (S. Matheus, B. Labeau, L. Berthelot, D. Rousset); Institut Pasteur de Dakar, Dakar, Senegal (C. Talla, M. Vray); French Armed Forces Health Service in French Guiana, Cayenne (F. de Laval); French Military Centre for Epidemiology and Public Health, Marseille, France (F. de Laval); Institut de Recherche Biomédicale des Armées, Marseille (S. Briolant); Aix Marseille Université, Marseille (S. Briolant)

Main Article

Table 1

Characteristics of panels evaluated in study of Zika virus diagnostic tests

Panel Sample characterization No. samples Mean time to collection after onset of fever, d (+ SD)
Panel performance evaluation 3–20 days after onset
Zika virus subgroup Positive Zika virus 90 10 + 6
Non–Zika virus subgroup Negative Zika virus with confirmed dengue virus infection 35 10 + 3
Negative Zika virus with confirmed chikungunya virus infection 29 13 + 3
Negative Zika virus, dengue virus, chikungunya virus 45 11 + 5
Total panel performance

10 + 5
Panel IgM–IgG kinetics 0–300 days after onset
Positive Zika virus 300* Minimum 0, maximum 300, median 20, interquartile range 4–81

*300 samples from 124 patients, including the 90 positive Zika virus samples in the first panel.

Main Article

Page created: May 20, 2019
Page updated: May 20, 2019
Page reviewed: May 20, 2019
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.