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Volume 26, Number 11—November 2020
Research

Modeling Treatment Strategies to Inform Yaws Eradication

Alex HolmesComments to Author , Michael J. Tildesley, Anthony W. Solomon, David C.W. Mabey, Oliver Sokana, Michael Marks, and Louise Dyson
Author affiliations: Mathematics Institute, University of Warwick, Coventry, UK (A. Holmes, M.J. Tildesley, L. Dyson); University of Warwick School of Life Sciences, Coventry (M.J. Tildesley, L. Dyson); Hospital for Tropical Diseases, London, UK (A.W. Solomon, D.C.W. Mabey, M. Marks); London School of Hygiene and Tropical Medicine, London (A.W. Solomon, D.C.W. Mabey, M. Marks); Ministry of Health and Medical Services, Honiara, Solomon Islands (O. Sokana)

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Figure 3

Dynamics of yaws transmission (clinical infectious and latent cases combined, averaged over 1,000 simulations) under 3 different treatment strategies: 2 TCT, 2 TTT (red); 3 TCT, 2 TTT (blue); 2 TCT, 3 TTT (green). A) All parameters tested; B) close-up showing detail of results. Simulations are run to steady state before starting the first round of treatment. Times given are the amount of time (in years) since the first round of treatment. Parameters are inferred from data collected from the Solomon Islands in 2013. TCT, total community treatment; TTT, total targeted treatment.

Figure 3. Dynamics of yaws transmission (clinical infectious and latent cases combined, averaged over 1,000 simulations) under 3 different treatment strategies: 2 TCT, 2 TTT (red); 3 TCT, 2 TTT (blue); 2 TCT, 3 TTT (green). A) All parameters tested; B) close-up showing detail of results. Simulations are run to steady state before starting the first round of treatment. Times given are the amount of time (in years) since the first round of treatment. Parameters are inferred from data collected from the Solomon Islands in 2013. TCT, total community treatment; TTT, total targeted treatment.

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Page created: August 18, 2020
Page updated: October 17, 2020
Page reviewed: October 17, 2020
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