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Volume 26, Number 11—November 2020
Research

Modeling Treatment Strategies to Inform Yaws Eradication

Alex HolmesComments to Author , Michael J. Tildesley, Anthony W. Solomon, David C.W. Mabey, Oliver Sokana, Michael Marks, and Louise Dyson
Author affiliations: Mathematics Institute, University of Warwick, Coventry, UK (A. Holmes, M.J. Tildesley, L. Dyson); University of Warwick School of Life Sciences, Coventry (M.J. Tildesley, L. Dyson); Hospital for Tropical Diseases, London, UK (A.W. Solomon, D.C.W. Mabey, M. Marks); London School of Hygiene and Tropical Medicine, London (A.W. Solomon, D.C.W. Mabey, M. Marks); Ministry of Health and Medical Services, Honiara, Solomon Islands (O. Sokana)

Main Article

Figure 8

Probability of local elimination of transmission under intervention strategy consisting of 2 rounds of TCT, followed by 2 rounds of TTT treating clinical cases and household contacts as correlation between treatment rounds varies. 0 correlation denotes random treatment, whereas a correlation of 1 denotes fully systematic treatment. Each twice-yearly round of TCT has 80% coverage, whereas TTT has 100% coverage, and treatment is assumed to have 95% efficacy. Parameters are inferred from data collected from the Solomon Islands in 2013. TCT, total community treatment; TTT, total targeted treatment.

Figure 8. Probability of local elimination of transmission under intervention strategy consisting of 2 rounds of TCT, followed by 2 rounds of TTT treating clinical cases and household contacts as correlation between treatment rounds varies. 0 correlation denotes random treatment, whereas a correlation of 1 denotes fully systematic treatment. Each twice-yearly round of TCT has 80% coverage, whereas TTT has 100% coverage, and treatment is assumed to have 95% efficacy. Parameters are inferred from data collected from the Solomon Islands in 2013. TCT, total community treatment; TTT, total targeted treatment.

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Page created: August 18, 2020
Page updated: October 17, 2020
Page reviewed: October 17, 2020
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