Volume 26, Number 12—December 2020
Research
Small Particle Aerosol Exposure of African Green Monkeys to MERS-CoV as a Model for Highly Pathogenic Coronavirus Infection
Allison Totura1, Virginia Livingston, Ondraya Frick, David Dyer, Donald Nichols, and Aysegul Nalca
Figure 1
Figure 1. Study schedule for small particle aerosol infection of African green monkeys (AGMs) with MERS-CoV. Three groups of AGMs (4 in each group) were exposed to 3 different target doses of MERS-CoV EMC/2012 strain by small particle aerosol exposure. AGMs were observed at indicated days postinfection (shown by squares) for metrics that would indicate recapitulation of MERS-CoV infection in humans. MERS-CoV, Middle East respiratory syndrome coronavirus.
1Current affiliation: US Department of Health and Human Services Biomedical Advanced Research and Development Authority, Washington, DC, USA
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