Volume 26, Number 12—December 2020
Research
Small Particle Aerosol Exposure of African Green Monkeys to MERS-CoV as a Model for Highly Pathogenic Coronavirus Infection
Allison Totura1, Virginia Livingston, Ondraya Frick, David Dyer, Donald Nichols, and Aysegul Nalca
Table 1
Inhaled doses of African green monkeys exposed to MERS-CoV*
| Animal ID | Sex | Target dose, 10x PFU | Actual dose, PFU | Actual dose, 10x PFU |
|---|---|---|---|---|
| 1 | F | 3 | 7.60 × 102 | 2.88 |
| 2 | M | 3 | 1.17 × 103 | 3.07 |
| 3 | M | 3 | 8.70 × 102 | 2.94 |
| 4 | F | 3 | 1.11 × 103 | 3.04 |
| 5 | F | 4 | 6.31 × 103 | 3.80 |
| 6 | M | 4 | 7.79 × 103 | 3.89 |
| 7 | M | 4 | 7.25 × 103 | 3.86 |
| 8 | F | 4 | 4.65 × 103 | 3.67 |
| 9 | F | 5 | 2.78 × 104 | 4.44 |
| 10 | M | 5 | 3.75 × 104 | 4.57 |
| 11 | M | 5 | 2.83 × 104 | 4.45 |
| 12 | F | 5 | 2.27 × 104 | 4.36 |
*MERS-CoV, Middle East respiratory syndrome coronavirus.
1Current affiliation: US Department of Health and Human Services Biomedical Advanced Research and Development Authority, Washington, DC, USA
Page created: July 22, 2020
Page updated: November 19, 2020
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