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Volume 26, Number 3—March 2020
Synopsis

Mycobacterium tuberculosis Complex Lineage 3 as Causative Agent of Pulmonary Tuberculosis, Eastern Sudan1

Yassir A. ShuaibComments to Author , Eltahir A.G. Khalil, Lothar H. Wieler, Ulrich E. Schaible, Mohammed A. Bakheit, Saad E. Mohamed-Noor, Mohamed A. Abdalla, Glennah Kerubo, Sönke Andres, Doris Hillemann, Elvira Richter, Katharina Kranzer, Stefan Niemann2, and Matthias Merker2Comments to Author 
Author affiliations: Freie Universität Berlin, Berlin, Germany (Y.A. Shuaib, L.H. Wieler); Research Center Borstel, Borstel, Germany (Y.A. Shuaib, U.E. Schaible, S. Andres, D. Hillemann, S. Niemann, M. Merker); Sudan University of Science and Technology, Khartoum, Sudan (Y.A. Shuaib, S.E. Mohamed-Noor, M.A. Abdalla); University of Khartoum, Khartoum, Sudan (E.A.G. Khalil, M.A. Bakheit); Robert Koch Institute, Berlin (L.H. Wieler); Kenyatta University, Nairobi, Kenya (G. Kerubo); Labor Limbach, Heidelberg, Germany (E. Richter); London School of Hygiene and Tropical Medicine, London, UK (K. Kranzer); German Center for Infection Research, Borstel Site, Borstel (S. Niemann, M. Merker)

Main Article

Figure 2

MTBC population structure in eastern Sudan. Maximum-likelihood tree based on 11,932 concatenated single-nucleotide polymorphisms (SNPs) using a general time-reversible substitution model. Colored bars code for (inner to outer ring) MTBC lineages (L1–4); genotypic DST results stratified to MDR, non-MDR, and pansusceptible; sampling location; and clustered and nonclustered strains (SNP distance ≤12). MDR, multidrug resistant; MTBC, Mycobacterium tuberculosis complex.

Figure 2. MTBC population structure in eastern Sudan. Maximum-likelihood tree based on 11,932 concatenated single-nucleotide polymorphisms (SNPs) using a general time-reversible substitution model. Colored bars code for (inner to outer ring) MTBC lineages (L1–4); genotypic DST results stratified to MDR, non-MDR, and pansusceptible; sampling location; and clustered and nonclustered strains (SNP distance ≤12). MDR, multidrug resistant; MTBC, Mycobacterium tuberculosis complex.

Main Article

1Preliminary results from this study were presented at the 39th Annual Congress of the European Society of Mycobacteriology, July 1–4, 2018, Dresden, Germany.

2These authors contributed equally to this article.

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Page updated: February 20, 2020
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