Cellular Immunity in COVID-19 Convalescents with PCR-Confirmed Infection but with Undetectable SARS-CoV-2–Specific IgG
Sina Schwarzkopf, Adalbert Krawczyk, Dietmar Knop, Hannes Klump, Andreas Heinold, Falko M. Heinemann, Laura Thümmler, Christian Temme, Marianne Breyer, Oliver Witzke, Ulf Dittmer, Veronika Lenz, Peter A. Horn, and Monika Lindemann
Author affiliations: Institute for Transfusion Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany (S. Schwarzkopf, D. Knop, H. Klump, A. Heinold, F.M. Heinemann, L. Thümmler, C. Temme, M. Breyer, V. Lenz, P.A. Horn, M. Lindemann); Department of Infectious Diseases, West German Centre of Infectious Diseases, Universitätsmedizin Essen, University of Duisburg-Essen, Essen (A. Krawczyk, O. Witzke); Institute for Virology, University Hospital Essen, University of Duisburg-Essen, Essen (U. Dittmer)
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Figure 1
Figure 1. Distribution of SARS-CoV-2 IgG in 78 potential convalescent-plasma donors with PCR-confirmed infection, Germany. Red dots represent study participants with antibody ratio >3; black dots, participants with a ratio of 1.1–3; blue dots, participants with ratio <1.1. Sequential data are connected. Horizontal dashed line indicates a ratio of 3. A) Antibody ratios in the positive or intermediate range. B) Antibody ratios in the borderline or negative range. Gray shading indicates borderline values (ratio of 0.8–1.1); scale is adjusted to enhance data visualization. SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.
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