Volume 27, Number 1—January 2021
Research
Cellular Immunity in COVID-19 Convalescents with PCR-Confirmed Infection but with Undetectable SARS-CoV-2–Specific IgG
Sina Schwarzkopf, Adalbert Krawczyk, Dietmar Knop, Hannes Klump, Andreas Heinold, Falko M. Heinemann, Laura Thümmler, Christian Temme, Marianne Breyer, Oliver Witzke, Ulf Dittmer, Veronika Lenz, Peter A. Horn, and Monika Lindemann
Table
Clinical characteristics of 78 potential convalescent-plasma donors with PCR-confirmed severe acute respiratory syndrome coronavirus 2 infection, grouped by antibody ratio, Germany*
| Parameter | Ratio <1.1 | Ratio 1.1–3.0 | Ratio >3.0 |
|---|---|---|---|
| All donors | 13 (16.7) | 24 (30.8) | 41 (52.6) |
| Age, y | 45 (19–55) | 51 (28–65) | 47 (20–66) |
| Sex, M/F | 6/7 | 19/5 | 29/12 |
| Body mass index | 25.2 (22.3–30.1) | 24.9 (22.8–28.1) | 26.7 (22.2–36.8) |
| Interval to onset of symptoms, d | 52 (32–100) | 60 (24–98) | 64 (22–112) |
| Stay in risk area/risk contact |
6 |
17 |
20 |
| Symptoms of COVID-19 infection | |||
| Cough | 7 | 19 | 30 |
| Fever | 9 | 13 | 24 |
| Shortage of air | 3 | 4 | 15 |
| Rhinitis | 7 | 7 | 16 |
| Sore throat | 6 | 8 | 15 |
| Limb pain | 7 | 15 | 19 |
| Shivering | 6 | 8 | 15 |
| Diarrhea | 5 | 6 | 15 |
| Weight loss | 3 | 2 | 9 |
| Nausea | 0 | 0 | 4 |
| Loss of appetite | 5 | 3 | 12 |
| Headaches | 7 | 16 | 26 |
| Skin rash | 1 | 1 | 1 |
| Swelling of lymph nodes | 3 | 0 | 2 |
| Loss of sense of smell and taste |
8 |
16 |
18 |
| Necessity of oxygen supply | 0 | 1 | 3 |
| Antimicrobial treatment |
1 |
3 |
7 |
| Blood group | |||
| O | 5 | 12 | 16 |
| A | 6 | 8 | 16 |
| B | 0 | 0 | 6 |
| AB | 1 | 3 | 3 |
| ND | 1 | 1 | 0 |
*Values are no. donors or median (range). Ratio is IgG against the S1 protein. ND, not determined.
Page created: October 15, 2020
Page updated: December 21, 2020
Page reviewed: December 21, 2020
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