Severe Acute Respiratory Syndrome Coronavirus 2 and Pregnancy Outcomes According to Gestational Age at Time of Infection
Dominique A. Badr, Olivier Picone, Elisa Bevilacqua, Andrew Carlin, Federica Meli, Jeanne Sibiude, Jérémie Mattern, Jean-François Fils, Laurent Mandelbrot, Antonio Lanzone, Danièle De Luca, Jacques C. Jani
, and Alexandre J. Vivanti
Author affiliations: University Hospital Brugmann, Brussels, Belgium (D.A. Badr, A. Carlin, J.C. Jani); Université Libre de Bruxelles, Brussels (D.A. Badr, A. Carlin, J.C. Jani); Louis Mourier Hospital, AP-HP, Colombes, France (O. Picone, J. Sibuide, L. Mandelbrot); Université de Paris, Paris, France (O. Picone, J. Sibuide, L. Mandelbrot); Inserm IAME-U1137, Paris (O. Picone, J. Sibuide, L. Mandelbrot); Groupe de Recherche sur les Infections pendant la Grossesse (GRIG), Velizy, France (O. Picone, J. Sibuide, L. Mandelbrot, A.J. Vivanti); Gemelli University Polyclinic Foundation, Rome, Italy (E. Bevilacqua, F. Melli, A. Lanzone); Antoine Béclère Hospital, AP-HP, Clamart, France (J. Mattern, A.J. Vivanti, D. De Luca); Paris Saclay University, Paris (J. Mattern, D. De Luca, A.J. Vivanti); Ars Statistica, Nivelles, Belgium (J.-F. Fils); Catholic University Sacro Cuore, Rome (A. Lanzone)
Figure 2. Kaplan-Meier curves demonstrating the effect of gestational age at the time of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on pregnancy outcomes in Europe. A) Compared with patients without CAOO, patients with CAOO were more often infected with SARS-CoV-2. The difference was seen when patients were infected at >20 weeks of gestation. B) Compared with patients without CANO, patients with CANO were more often infected with SARS-CoV-2. The difference was seen when patients were infected at >26 weeks of gestation. Numbers below x-axis indicate number of persons at risk for each time point. CANO, composite adverse neonatal outcome; CAOO, composite adverse obstetric outcome.
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