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Volume 27, Number 11—November 2021

Genetically Divergent Highly Pathogenic Avian Influenza A(H5N8) Viruses in Wild Birds, Eastern China

Guimei He, Le Ming, Xiang Li, Yuhe Song, Ling Tang, Min Ma, Jie CuiComments to Author , and Tianhou WangComments to Author 
Author affiliations: East China Normal University, Shanghai, China (G. He, L. Ming, L. Tang, M. Ma, T. Wang); CAS Key Laboratory of Molecular Virology & Immunology, Institut Pasteur, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Shanghai (X. Li, Y. Song, J. Cui)

Main Article


Nucleotide sequence identity of 5 representative avian influenza A(H5N8) isolates from 5 different host species, Shanghai, China, 2020

Isolates Gene segment Homologous strains* GISAID accession no. Identity, %
Polymerase basic 2 protein A/duck/Korea/H439/2020 (A/H5N8) EPI1845982 99.9
Polymerase basic 1 protein A/duck/Korea/H439/2020 (H5N8) EPI1845983 99.9
Polymerase acidic protein A/northern pintail/Hokkaido/M13/2020(H5N8) EPI1818401 99.7
Hemagglutinin A/duck/Korea/H439/2020 (A/H5N8) EPI1845985 99.8
Nucleoprotein A/duck/Korea/H439/2020 (A/H5N8) EPI1845978 99.3
Neuraminidase A/ duck/Korea/H439/2020 (A/H5N8) EPI1845984 99.9
Matrix protein A/chicken/Kagawa/11C/2020(H5N8) EPI1815028 99.8
Nonstructural protein
Polymerase basic 2 protein A/wild duck/Korea/H331/2020 (H5N8) EPI1846695 99.6
A/spot-billed duck/Korea/WA1000/2020 (H5N8) EPI1846695 99.6
Polymerase basic 1 protein A/quail/Korea/H440/2020 (H5N8) EPI1846512 99.7
A/chicken/Korea/H440/2020 (H5N8) EPI1845991 99.7
Polymerase acidic protein A/chicken/Omsk/0119/2020 (H5N8) EPI1813381 99.9
A/domestic duck/kazakhstan/1–274–20-B/2020 (H5N8) EPI1811610 99.9
Hemagglutinin A/chicken/Korea/H544/2020 (H5N8) EPI1850622 100.0
A/chicken/Korea/H001/2021 (H5N8) EPI1846522 100.0
Nucleoprotein A/mallard/Kagoshima/ KU-d89/2021 (H5N8) EPI1846675 99.9
A/spot-billed duck/Korea/Wa1000/2020 (H5N8) EPI1846697 99.9
Neuraminidase A/wild duck/Korea/H331/2020 (H5N8) EPI1850682 99.9
A/chicken/Korea/H002/2021 (H5N8) EPI1846529 99.9
Matrix protein A/wild bird/Korea/H496–3/2020 (H5N8) EPI1857465 100.0
A/chicken/Korea/H544/2020 (H5N8) EPI1850662 100.0
Nonstructural protein A/Greylag_goose/England/033100/2020 (A/H5N8) EPI1837929 99.8
A/turkey/Omsk/0003/2020 (H5N8) EPI1846695 99.8

*List comprises the most or the 2 most homologous viruses available in GISAID ( for each gene segment.

Main Article

Page created: August 09, 2021
Page updated: October 19, 2021
Page reviewed: October 19, 2021
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