Volume 27, Number 4—April 2021
Research
Histopathological Characterization of Cases of Spontaneous Fatal Feline Severe Fever with Thrombocytopenia Syndrome, Japan
Yusuke Sakai
, Yuko Kuwabara, Keita Ishijima1, Saya Kagimoto, Serina Mura, Kango Tatemoto1, Ryusei Kuwata2, Kenzo Yonemitsu1, Shohei Minami, Yudai Kuroda1, Kenji Baba, Masaru Okuda, Hiroshi Shimoda, Masashi Sakurai, Masahiro Morimoto, and Ken Maeda1
, Yuko Kuwabara, Keita Ishijima1, Saya Kagimoto, Serina Mura, Kango Tatemoto1, Ryusei Kuwata2, Kenzo Yonemitsu1, Shohei Minami, Yudai Kuroda1, Kenji Baba, Masaru Okuda, Hiroshi Shimoda, Masashi Sakurai, Masahiro Morimoto, and Ken Maeda1
Table 1
Clinicopathological findings in 7 cats with fatal severe fever with thrombocytopenia syndrome, Japan*
| Clinical findings |
Case no. |
||||||
| 1 |
2 |
3 |
4 |
5 |
6 |
7 |
|
| Clinical signs | |||||||
| Anorexia | Y | Y | Y | Y | Y | Y | Y |
| Lethargy | Y | Y | Y | Y | Y | Y | Y |
| Neurologic signs | N | N | N | Y | N | N | N |
| Vomiting |
N |
Y |
N |
N |
N |
Y |
N |
| Body temperature, °C | 39.4 | NA | NA | NA | 39.3 | 39.9 | 39 |
| Erythrocytes, 104 cells/μL | 546 | 688 | NA | 364 | 718 | 820 | 593 |
| Leukocytes, cells/μL | 3,080 | 800 | 3,000 | 190 | 700 | 2,500 | 1,290 |
| Platelets, cells/μL | 38,000 | 7,000 | 0 | 0 | <11,000 | 52,000 | 0 |
| ALT, IU/L | 105 | NA | 476 | 141 | 331 | NA | 58 |
| AST, IU/L | 51 | NA | >1,000 | 4 | 1,010 | NA | NA |
| ALP, IU/L | 188 | NA | NA | NA | NA | NA | <10 |
| Total bilirubin, mg/dL | 4.4 | 5.8 | 4.8 | 5.7 | NA | NA | 9.3 |
| CPK, IU/L |
NA |
373 |
>2,000 |
>2,000 |
1,444 |
NA |
NA |
| *ALP, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CPK, creatine phosphokinase; NA, not available. | |||||||
1Current affiliation: National Institute of Infectious Diseases, Tokyo, Japan.
2Current affiliation: Okayama University of Science, Ehime, Japan.
Page created: February 17, 2021
Page updated: March 18, 2021
Page reviewed: March 18, 2021
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