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Volume 28, Number 5—May 2022
Research

Risk for Asymptomatic Household Transmission of Clostridioides difficile Infection Associated with Recently Hospitalized Family Members

Aaron C. MillerComments to Author , Alan T. Arakkal, Daniel K. Sewell, Alberto M. Segre, Sriram V. Pemmaraju, Philip M. Polgreen, and CDC MInD-Healthcare Group
Author affiliation: University of Iowa, Iowa City, Iowa, USA

Main Article

Table 1

Baseline enrollment characteristics of families with multiple infected members using a 60-day exposure window in study of asymptomatic Clostridioides difficile transmission among household members, United States*

Characteristics
All enrollees. no. (%)
No. (%) episodes of index CDI diagnosis†
No. (%) cases of possible transmission after family member hospitalization
No. CDI cases NA 224,818 6,575
No. enrollees
142,125,247 (100)
194,424 (100)
6,453 (100)
Age group at enrollment or CDI diagnosis, y
0–17 47,733,847 (33.6) 19,719 (8.8) 547 (8.3)
18–40 46,634,859 (32.8) 37,259 (16.6) 1,156 (17.6)
41–65 44,039,682 (31.0) 103,430 (46.0) 1,822 (27.7)
>65
3,716,859 (2.6)
64,410 (28.6)
3,050 (46.4)
Sex
M 70,485,475 (49.6) 99,133 (44.1) 2,798 (42.6)
F
71,639,772 (50.4)
125,685 (55.9)
3,777 (57.4)
Family size
2 36,598,138 (25.8) 134,644 (59.9) 4,166 (63.4)
3 29,857,746 (21.0) 36,236 (16.1) 905 (13.8)
4 40,705,784 (28.6) 34,559 (15.4) 839 (12.8)
5 21,536,725 (15.2) 13,517 (6.0) 409 (6.2)
>5 13,426,854 (9.4) 5,862 (2.6) 256 (3.9)

*CDI, Clostridioides difficile infection; NA, not applicable. †Events occurring >60 days before another episode.

Main Article

Page created: March 08, 2022
Page updated: April 19, 2022
Page reviewed: April 19, 2022
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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