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Volume 28, Number 6—June 2022
Research

Geographic Origin and Vertical Transmission of Leishmania infantum Parasites in Hunting Hounds, United States

Susanne U. FranssenComments to Author , Mandy J. Sanders, Matt Berriman, Christine A. Petersen1, and James A. Cotton1
Author affiliations: Ludwig-Maximilians-Universität Munich, Munich, Germany (S.U. Franssen); Wellcome Sanger Institute, Hinxton, UK (S.U. Franssen, M.J. Sanders, M. Berriman, J.A. Cotton); University of Iowa College of Public Health, Iowa City, Iowa, USA (C.A. Petersen); Center for Emerging Infectious Diseases, University of Iowa, Iowa City (C.A. Petersen)

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Figure 2

Geographic origin of US hound Leishmania isolates. A) Cladogram of the neighbor-joining tree from Figure 1 showing monophyletic groups for better visibility of evolutionary relationships of the US hound parasites. B) Cladogram of the maximum-likelihood phylogeny (Appendix 2 Figure 2, panel B). Cladograms were reconstructed on the basis of whole-genome genotype calls of 83 parasite samples representing the dominant L. infantum zymodeme MON-1 from the United States, Europe, South America, and the Middle East, which were the samples most relevant in the context of the origin of the US samples (Appendix 2 Figure 2). Numbers at internal nodes show bootstrap values.

Figure 2. Geographic origin of US hound Leishmania isolates. A) Cladogram of the neighbor-joining tree from Figure 1 showing monophyletic groups for better visibility of evolutionary relationships of the US hound parasites. B) Cladogram of the maximum-likelihood phylogeny (Appendix 2 Figure 2, panel B). Cladograms were reconstructed on the basis of whole-genome genotype calls of 83 parasite samples representing the dominant L. infantum zymodeme MON-1 from the United States, Europe, South America, and the Middle East, which were the samples most relevant in the context of the origin of the US samples (Appendix 2 Figure 2). Numbers at internal nodes show bootstrap values.

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1These senior authors contributed equally to this article.

Page created: April 12, 2022
Page updated: May 22, 2022
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