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Volume 28, Number 6—June 2022
Research

Geographic Origin and Vertical Transmission of Leishmania infantum Parasites in Hunting Hounds, United States

Susanne U. FranssenComments to Author , Mandy J. Sanders, Matt Berriman, Christine A. Petersen1, and James A. Cotton1
Author affiliations: Ludwig-Maximilians-Universität Munich, Munich, Germany (S.U. Franssen); Wellcome Sanger Institute, Hinxton, UK (S.U. Franssen, M.J. Sanders, M. Berriman, J.A. Cotton); University of Iowa College of Public Health, Iowa City, Iowa, USA (C.A. Petersen); Center for Emerging Infectious Diseases, University of Iowa, Iowa City (C.A. Petersen)

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Figure 5

Extreme excess of heterozygous sites in the US hound–derived Leishmania infantum isolates. The group-specific inbreeding coefficient F is shown for all polymorphic sites in the respective parasite population. F measures the deviation of the frequency of heterozygotes from Hardy-Weinberg equilibrium with negative values indicating an excess and positive values a deficiency of heterozygotes over homozygotes. Horizontal lines within boxes indicate medians; box top and bottom lines indicate 25 and 75 percentiles; and error bars indicate minimum and maximum values, excluding outliers.

Figure 5. Extreme excess of heterozygous sites in the US hound–derived Leishmania infantum isolates. The group-specific inbreeding coefficient F is shown for all polymorphic sites in the respective parasite population. F measures the deviation of the frequency of heterozygotes from Hardy-Weinberg equilibrium with negative values indicating an excess and positive values a deficiency of heterozygotes over homozygotes. Horizontal lines within boxes indicate medians; box top and bottom lines indicate 25 and 75 percentiles; and error bars indicate minimum and maximum values, excluding outliers.

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1These senior authors contributed equally to this article.

Page created: April 12, 2022
Page updated: May 22, 2022
Page reviewed: May 22, 2022
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