Figure 1. Flowchart of steps used for identifying dominant carbapenemase-encoding plasmids in clinical Enterobacterales isolates and hypervirulent Klebsiella pneumoniae, Singapore. We collected 1,312 samples available in the CaPES collection and analyzed 1,215 whole-genome sequenced samples. We identified 2 dominant clusters with large numbers of carbapenemase-encoding plasmids; the blaKPC–dominant cluster comprised pKPC2 plasmids and the blaNDM–dominant cluster pNDM1 plasmids. CaPES, Carbapenemase-Producing Enterobacteriaceae in Singapore (CaPES) (Enterobacteriaceae is the former name of Enterobacterales); WGS, whole-genome sequencing.