Figure 2. Percentage and distribution of dominant carbapenemase-encoding plasmids in clinical Enterobacterales isolates and hypervirulent Klebsiella pneumoniae, Singapore. A) Percentage distribution of the total carbapenemase-encoding plasmids identified. The blaKPC dominant cluster refers to those harboring pKPC2 plasmid; blaNDM dominant cluster refers to those harboring pNDM1 plasmid. Others indicate carbapenemase-encoding plasmids that do not carry blaKPC or blaNDM. B, C) Distribution of carbapenemase-encoding plasmids identified among Carbapenemase-Producing Enterobacteriaceae in Singapore (CaPES) (Enterobacteriaceae is the former name of Enterobacterales) samples collected during September 2010–March 2015 (B) and among Enterobacterales isolates (C). Nondominant cluster refers to other plasmids carrying blaKPC or blaNDM. We found that pKPC2 was the most dominant carbapenemase-encoding plasmid in Singapore during 2010–2015.