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Volume 28, Number 8—August 2022
Research

Dominant Carbapenemase-Encoding Plasmids in Clinical Enterobacterales Isolates and Hypervirulent Klebsiella pneumoniae, Singapore

Melvin Yong, Yahua Chen, Guodong Oo, Kai Chirng Chang, Wilson H.W. Chu, Jeanette Teo, Indumathi Venkatachalam, Natascha May Thevasagayam, Prakki S. Rama Sridatta, Vanessa Koh, Andrés E. Marcoleta, Hanrong Chen, Niranjan Nagarajan, Marimuthu Kalisvar, Oon Tek Ng, and Yunn-Hwen GanComments to Author 
Author affiliations: National University of Singapore, Singapore (M. Yong, Y. Chen, G. Oo, K.C. Chang, W.H.W. Chu, N. Nagarajan, M. Kalisvar, Y.-H. Gan); National University Hospital, Singapore (J. Teo); Singapore General Hospital, Singapore (I. Venkatachalam); National Centre for Infectious Diseases, Singapore (N.M. Thevasagayam, P.S.R. Sridatta, V. Koh, M. Kalisvar, O.T. Ng); Tan Tock Seng Hospital, Singapore (V. Koh, M. Kalisvar, O.T. Ng); Universidad de Chile, Santiago, Chile (A.E. Marcelota); Genome Institute of Singapore, Singapore (H. Chen, N. Nagarajan); Nanyang Technological University, Singapore (O.T. Ng)

Main Article

Figure 5

Plasmid incompatibility group analysis of pKPC2 carbapenemase-encoding plasmid in clinical Enterobacterales isolates and hypervirulent Klebsiella pneumoniae, Singapore. A) Stability of pKPC2KmR in Escherichia coli MG1655 harboring pRK2-AraE plasmid from IncP incompatibility group. Symbols indicate means and error bars indicate SDs from 3 independent experiments. B) Phylogenetic comparison of pKPC2 trfA replicon with other IncP plasmids among isolates. Scale bar indicates nucleotide substitutions per site.

Figure 5. Plasmid incompatibility group analysis of pKPC2 carbapenemase-encoding plasmid in clinical Enterobacterales isolates and hypervirulent Klebsiella pneumoniae, Singapore. A) Stability of pKPC2KmR in Escherichia coli MG1655 harboring pRK2-AraE plasmid from IncP incompatibility group. Symbols indicate means and error bars indicate SDs from 3 independent experiments. B) Phylogenetic comparison of pKPC2 trfA replicon with other IncP plasmids among isolates. Scale bar indicates nucleotide substitutions per site.

Main Article

Page created: June 22, 2022
Page updated: July 20, 2022
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