Dominant Carbapenemase-Encoding Plasmids in Clinical Enterobacterales Isolates and Hypervirulent Klebsiella pneumoniae, Singapore
Melvin Yong, Yahua Chen, Guodong Oo, Kai Chirng Chang, Wilson H.W. Chu, Jeanette Teo, Indumathi Venkatachalam, Natascha May Thevasagayam, Prakki S. Rama Sridatta, Vanessa Koh, Andrés E. Marcoleta, Hanrong Chen, Niranjan Nagarajan, Marimuthu Kalisvar, Oon Tek Ng, and Yunn-Hwen Gan
Author affiliations: National University of Singapore, Singapore (M. Yong, Y. Chen, G. Oo, K.C. Chang, W.H.W. Chu, N. Nagarajan, M. Kalisvar, Y.-H. Gan); National University Hospital, Singapore (J. Teo); Singapore General Hospital, Singapore (I. Venkatachalam); National Centre for Infectious Diseases, Singapore (N.M. Thevasagayam, P.S.R. Sridatta, V. Koh, M. Kalisvar, O.T. Ng); Tan Tock Seng Hospital, Singapore (V. Koh, M. Kalisvar, O.T. Ng); Universidad de Chile, Santiago, Chile (A.E. Marcelota); Genome Institute of Singapore, Singapore (H. Chen, N. Nagarajan); Nanyang Technological University, Singapore (O.T. Ng)
Main Article
Table
Regression coefficients for pKPC2 and pNDM1 plasmid conjugation frequencies between donor-recipient pairs in a study of carbapenemase-encoding plasmids in clinical Enterobacterales isolates and hypervirulent Klebsiella pneumoniae, Singapore*
Taxonomic relatedness (model parameter) |
pKPC2
|
|
pNDM1
|
Mean |
Bootstrap 95% CI |
Mean |
Bootstrap 95% CI |
Same strain (β0) |
−1.73 |
−1.824 to −1.610 |
|
−2.31 |
−2.405 to −2.212 |
Same species (β1) |
−1.38 |
−1.599 to −1.147 |
|
−1.56 |
−1.771 to −1.317 |
Same genus (β2) |
−1.01 |
−1.162 to −0.866 |
|
−2.09 |
−2.258 to −1.907 |
Different genus (β3) |
0.04 |
−0.1165 to 0.1988 |
|
−1.94 |
−2.086 to −1.808 |
Main Article
Page created: June 22, 2022
Page updated: July 20, 2022
Page reviewed: July 20, 2022
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