Clinical Manifestations and Genomic Evaluation of Melioidosis Outbreak among Children after Sporting Event, Australia
Simon Smith
, Tonia Marquardt, Amy V. Jennison, Andrew D’Addona, James Stewart, Trent Yarwood, Jennifer Ho, Enzo Binotto, Julian Harris, Mark Fahmy, Juliet Esmonde, Megan Richardson, Rikki M.A. Graham, Richard Gair, Lawrence Ariotti, Annie Preston-Thomas, Sally Rubenach, Siobhan O’Sullivan, Darren Allen, Thomas Ragh, Sachjuan Grayson, Sophie Manoy, Jeffery M. Warner, Ella M. Meumann, Jennifer M. Robson, and Josh Hanson
Author affiliations: Cairns Hospital, Cairns, Queensland, Australia (S. Smith, J. Stewart, T. Yarwood, J. Ho, E. Binotto, J. Harris, M. Fahmy, S. O’Sullivan, T. Ragh, S. Grayson, S. Manoy, J. Hanson); Cairns & Hinterland Health Service, Cairns (T. Marquardt, A. D’Addona, J. Esmonde, M. Richardson, R. Gair, A. Preston-Thomas, S. Rubenach); Forensic and Scientific Services, Brisbane, Queensland, Australia (A.V. Jennison, R.M.A. Graham, L. Ariotti); University of Queensland, Herston, Queensland, Australia (T. Yarwood); James Cook University, Cairns (T. Yarwood, J. Ho); Royal Brisbane and Women’s Hospital, Brisbane, Queensland, Australia (D. Allen); James Cook University, Townsville, Queensland, Australia (J.M. Warner); Sullivan Nicolaides Pathology, Bowen Hills, Queensland, Australia (E.M. Meumann, J.M. Robson); Menzies School of Health Research, Darwin, Northern Territory, Australia (E.M. Meumann); University of New South Wales, Sydney, Australia (J. Hanson)
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Figure 1
Figure 1. Timeline of clinical manifestations and treatment of melioidosis among 7 children after sporting event, Australia. Limited cutaneous melioidosis developed in children after crawling through a mud pit on an obstacle course in a tropical region of Queensland. All children experienced an adverse drug reaction to trimethoprim/sulfamethoxazole, the preferred oral antimicrobial agent. All case-patients had good clinical outcomes, suggesting that a shorter duration of antimicrobial drugs might be appropriate for limited cutaneous melioidosis in some children.
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