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Volume 30, Number 11—November 2024
Research

Detection in Orchards of Predominant Azole-Resistant Candida tropicalis Genotype Causing Human Candidemia, Taiwan

Kuo-Yun Tseng1, Yin-Zhi Chen1, Zi-Li Zhou, Jyh-Nong Tsai, Min-Nan Tseng, Hsing-Lung Liu, Chi-Jung Wu, Yu-Chieh Liao, Chih-Chao Lin, De-Jiun Tsai, Feng-Jui Chen, Li-Yun Hsieh, Kuan-Chung Huang, Chun-Hua Huang, Kai-Ting Chen, Wen-Li Chu, Chiao-Mei Lin, Shu-Man Shih, Chao Agnes Hsiung, Yee-Chun Chen, Huey-Kang Sytwu, Yun-Liang Yang, and Hsiu-Jung LoComments to Author 
Author affiliation: National Tsing Hua University, Hsinchu, Taiwan (K.-Y. Tseng); National Health Research Institutes, Miaoli, Taiwan (K.-Y. Tseng, Y.-Z. Chen, Z.-L. Zhou, C.-J. Wu, Y.-C. Liao, C.-C. Lin, D.-J. Tsai, F.-J. Chen, L.-Y. Hsieh, K.-C. Huang, C.-H. Huang, K.-T. Chen, W.-L. Chu, C.-M. Lin, S.-M. Shih, C.A. Hsiung, Y.-C. Chen, H.-K. Sytwu, H.-J. Lo); National Yang Ming Chiao Tung University, Hsinchu (Z.-L. Zhou, Y.-L. Yang, H.-J. Lo); Taiwan Agricultural Research Institute, Taichung, Taiwan (J.-N. Tsai); Kaohsiung District Agricultural Research and Extension Station, Pingtung, Taiwan (M.-N. Tseng); Taichung District Agricultural Research and Extension Station, CHangHua, Taiwan (H.-L. Liu); National Cheng Kung University Hospital and Medical College, Tainan, Taiwan (C.-J. Wu); National Taiwan University Hospital College of Medicine, Taipei, Taiwan (Y.-C. Chen); China Medical University, Taichung (H.-J. Lo)

Main Article

Table 2

Correlations between susceptibilities to fluconazole and 3 fungicides in study of detection in orchards of predominant azole-resistant Candida tropicalis genotype causing human candidemia, Taiwan*

Fungicide MICs, mg/L Fluconazole MICs, mg/L
 Total no. Spearman ρ p value
<2 4 8 16 32 >64
Difenoconazole 0.636 <0.001
<1 41 14 1 0 2 0 58
2 0 0 0 1 2 1 4
4 0 0 0 0 1 0 1
>8
 0
 0
 0
 0
 1
 2
 3
Tebuconazole 0.758 <0.001
<1 41 13 0 0 0 0 54
2 0 1 1 1 5 1 9
4 0 0 0 0 1 1 2
>8
 0
 0
 0
 0
 0
 1
 1
Triadimenol 0.875 <0.001
<2 36 1 0 0 0 0 37
4 1 0 0 0 0 0 1
8 2 3 1 1 0 0 7
16 2 9 0 0 0 0 11
32 0 1 0 0 0 0 1
>64 0 0 0 0 6 3 9

*Values are numbers of C. tropicalis isolates except as indicated. Spearman correlation coefficients were used to determine correlations between fluconazole susceptibility and susceptibility to 3 different fungicides used in agriculture in Taiwan.

Main Article

1These authors contributed equally to this article.

Page created: September 04, 2024
Page updated: November 01, 2024
Page reviewed: November 01, 2024
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