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Volume 30, Number 12—December 2024
Research

Rio Mamore Hantavirus Endemicity, Peruvian Amazon, 2020

Marta Piche-Ovares, Maria Paquita García, Andres Moreira-Soto, Maribel Dana Figueroa-Romero, Nancy Susy Merino-Sarmiento, Adolfo Ismael Marcelo-Ñique, Edward Málaga-Trillo, Dora Esther Valencia Manosalva, Miladi Gatty-Nogueira, César Augusto Cabezas Sanchez, and Jan Felix DrexlerComments to Author 
Author affiliation: Charité-Universitätsmedizin Berlin, Berlin, Germany (M. Piche-Ovares, A. Moreira-Soto, J.F. Drexler); Instituto Nacional de Salud, Lima, Peru (M. Paquita García, M.D. Figueroa-Romero, N.S. Merino-Sarmiento, A.I. Marcelo-Ñique, C.A. Cabezas Sanchez); Universidad Nacional, Heredia, Costa Rica (A. Moreira-Soto); Universidad Peruana Cayetano, Lima (E. Málaga-Trillo); Laboratorio de Referencia Regional de Salud Pública, Lambayeque, Peru (D.E. Valencia Manosalva); Laboratorio de Referencia Regional de Salud Pública, Loreto, Peru (M. Gatty-Nogueira); German Centre for Infection Research, Berlin, Germany (J.F. Drexler)

Main Article

Table 2

Results of complementary ELISA and PCR testing of hantavirus IgM serum samples positive by ELISA, Peru, January 2020–2021*

Sample IgM ELISA ratio†
 PCR copies/mL
 Non–antigen coated plate OD
CCHFV CHIKV MAYV OROV Plasmodium spp. EBV CMV
1395‡ 1.19 1.59 1.46 0.89 Negative Negative Negative 0.19
3261 5.38 5.91 5.61 5.94 Negative Negative Negative 0.80
3265 1.82 1.10 0.75 1.30 8.4 × 105 4.4 × 103 1.9 × 103 0.93
3281 1.97 2.82 3.75 6.50 Negative Negative Negative 0.73
3345 2.97 7.55 6.56 2.96 Negative Negative 4.2 × 103 0.86
3358 7.95 10.86 10.25 9.11 2.8 × 104 Negative Negative 0.88
3376 0.34 0.65 0.80 0.60 Negative Negative Negative 0.26
3630 3.61 3.80 2.17 1.30 Negative Negative Negative 0.64
4242‡ 2.43 1.74 1.47 1.97 Negative Negative Negative 0.77
4432 0.32 0.45 0.33 0.31 Negative Negative Negative 0.15
4605 1.28 1.74 2.63 11.04 Negative Negative Negative 0.50
4893 1.22 2.44 1.81 1.90 Negative Negative Negative 0.61

*Boldface indicates samples that tested positive. CCHFV, Crimean-Congo hemorrhagic fever virus; CHIKV, chikungunya virus; CMV, cytomegalovirus; EBV, Epstein-Barr virus; MAYV, Mayaro virus; OROV, Oropouche virus. The sample that tested positive by reverse transcription PCR was not tested because of limited sample volume after isolation attempts. OD of the negative control for IgM in Sin Nombre virus/Andes virus ELISA on a noncoated plate, 0.15. (Mann-Whitney U test, MAYV, U = 44; OROV, U = 56; CCHFV, U = 20, CHIKV, U = 15, p<0.001 for all). †Boldface indicates results with a ratio >1.1 considered positive in all ELISAs. ‡Samples that tested positive by hantavirus IFA.

Main Article

Page created: October 25, 2024
Page updated: November 26, 2024
Page reviewed: November 26, 2024
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