Disclaimer: Early release articles are not considered as final versions. Any changes will be reflected in the online version in the month the article is officially released.
Volume 30, Number 6—June 2024
Dispatch
Concurrent Infection with Clade 2.3.4.4b Highly Pathogenic Avian Influenza H5N6 and H5N1 Viruses, South Korea, 2023
Table 2
Nucleotide sequence identities of gene segments between the clade 2.3.4.4b HPAI H5N1 virus from a duck farm in South Korea, 2023, compared with A/duck/Korea/D448-N1/2023(H5N1) virus and the closest referent in the GISAID database*
| Gene | Virus† | GISAID accession no. | % Identity | Sample date | H5 clade |
|---|---|---|---|---|---|
| PB2 | A/large-billed_crow/Hokkaido/B067/2023(H5N1) | EPI_ISL_18591747 | 99.78 | 2023 Sep 23 | 2.3.4.4b |
| PB1 | A/Eurasian_wigeon/Kagoshima/4611J002/2023(H5N1) | EPI_ISL_18603583 | 99.87 | 2023 Sep 12 | 2.3.4.4b |
| PA | A/goose/Magadan/2272–5/2022(H5N1) | EPI_ISL_18071580 | 99.81 | 2022 Oct 09 | 2.3.4.4b |
| HA | A/Eurasian_wigeon/Kagoshima/4611J002/2023(H5N1) | EPI_ISL_18603583 | 99.53 | 2023 Sep 12 | 2.3.4.4b |
| NP | A/large-billed_crow/Hokkaido/0103E088/2023(H5N1) | EPI_ISL_17950087 | 99.87 | 2023 Mar 30 | 2.3.4.4b |
| NA | A/canada_goose/BC/AIVPHL-371/2023(H5N1) | EPI_ISL_17051482 | 99.79 | 2023 Jan 16 | 2.3.4.4b |
| M | A/northern_pintail/Okayama/331A003/2023(H5N1) | EPI_ISL_18603584 | 99.9 | 2023 Sep 13 | 2.3.4.4b |
| NS | A/Barnacle_Goose/Netherlands/8/2022(H5N1) | EPI_ISL_10347219 | 99.76 | 2022 Jan 28 | 2.3.4.4b |
*Two A/duck/Korea/D448-N1/2023(H5N1) isolates from poultry (D448-N1, D502) had high nucleotide identities between them in all 8 genes, PB2, 99.52%; PB1, 99.78%; PA, 99.72%; HA, 99.30%; NP, 99.73%; NA, 99.22%; M, 99.80%; NS, 99.05%. GISAID, https://www.gisaid.org; HA, hemagglutinin; HPAI, high pathogenicity avian influenza; M, matrix protein; N, nucleocapsid protein; NA, neuraminidase; NP, nucleoprotein; NS, nonstructural protein; PA, polymerase acidic protein; PB, polymerase basic protein. †All the viruses compared were isolated from wild birds.