Volume 30, Number 6—June 2024
Dispatch
Concurrent Infection with Clade 2.3.4.4b Highly Pathogenic Avian Influenza H5N6 and H5N1 Viruses, South Korea, 2023
Table 2
Nucleotide sequence identities of gene segments between the clade 2.3.4.4b HPAI H5N1 virus from a duck farm in South Korea, 2023, compared with A/duck/Korea/D448-N1/2023(H5N1) virus and the closest referent in the GISAID database*
| Gene | Virus† | GISAID accession no. | % Identity | Sample date | H5 clade |
|---|---|---|---|---|---|
| PB2 | A/large-billed_crow/Hokkaido/B067/2023(H5N1) | EPI_ISL_18591747 | 99.78 | 2023 Sep 23 | 2.3.4.4b |
| PB1 | A/Eurasian_wigeon/Kagoshima/4611J002/2023(H5N1) | EPI_ISL_18603583 | 99.87 | 2023 Sep 12 | 2.3.4.4b |
| PA | A/goose/Magadan/2272–5/2022(H5N1) | EPI_ISL_18071580 | 99.81 | 2022 Oct 09 | 2.3.4.4b |
| HA | A/Eurasian_wigeon/Kagoshima/4611J002/2023(H5N1) | EPI_ISL_18603583 | 99.53 | 2023 Sep 12 | 2.3.4.4b |
| NP | A/large-billed_crow/Hokkaido/0103E088/2023(H5N1) | EPI_ISL_17950087 | 99.87 | 2023 Mar 30 | 2.3.4.4b |
| NA | A/canada_goose/BC/AIVPHL-371/2023(H5N1) | EPI_ISL_17051482 | 99.79 | 2023 Jan 16 | 2.3.4.4b |
| M | A/northern_pintail/Okayama/331A003/2023(H5N1) | EPI_ISL_18603584 | 99.9 | 2023 Sep 13 | 2.3.4.4b |
| NS | A/Barnacle_Goose/Netherlands/8/2022(H5N1) | EPI_ISL_10347219 | 99.76 | 2022 Jan 28 | 2.3.4.4b |
*Two A/duck/Korea/D448-N1/2023(H5N1) isolates from poultry (D448-N1, D502) had high nucleotide identities between them in all 8 genes, PB2, 99.52%; PB1, 99.78%; PA, 99.72%; HA, 99.30%; NP, 99.73%; NA, 99.22%; M, 99.80%; NS, 99.05%. GISAID, https://www.gisaid.org; HA, hemagglutinin; HPAI, highly pathogenic avian influenza; M, matrix protein; N, nucleocapsid protein; NA, neuraminidase; NP, nucleoprotein; NS, nonstructural protein; PA, polymerase acidic protein; PB, polymerase basic protein. †All the viruses compared were isolated from wild birds.