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Volume 30, Number 8—August 2024
Research
Environmental Hot Spots and Resistance-Associated Application Practices for Azole-Resistant Aspergillus fumigatus, Denmark, 2020–2023
Maiken Cavling Arendrup
, Rasmus Krøger Hare, Karin Meinike Jørgensen, Ulla E. Bollmann, Tina B. Bech, Cecilie Cetti Hansen, Thies M. Heick, and Lise Nistrup Jørgensen
, Rasmus Krøger Hare, Karin Meinike Jørgensen, Ulla E. Bollmann, Tina B. Bech, Cecilie Cetti Hansen, Thies M. Heick, and Lise Nistrup Jørgensen
Table 2
Overview of Cyp51A and Hmg1 genotypes of azole-resistant Aspergillus fumigatus isolates, sorted by susceptibility classification, Denmark, 2020–2022
| Susceptibility classification and A. fumigatus protein alterations | No. genotypes |
|---|---|
| 38 azole-susceptible comparator isolates: 20 Cyp51A wild types | 37 |
| 6 F46Y/M172V/E427K | |
| 1 M172V | |
| 1 I242V |
*Isolates that were resistant for >1 triazoles on >1 MIC determination. †From flower bed in a private garden in 2021, flower pot soil in 2021, green waste and garden waste compost heaps in 2022, and from field soil in 2022. ‡From flower bed in another private garden in 2021. §From flower bed in a public park 2021, horse manure heap in 2022. ¶From flower pot soil in 2021.
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