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Volume 31, Number 11—November 2025

Research

Isolation and Characterization of Rickettsia finnyi, Novel Pathogenic Spotted Fever Group Rickettsia in Dogs, United States

Praveen K. Korla1, Michael G. Karounos1, Sarah B. Clarke, Cynthia Robveille, James M. Wilson, Edward B. Breitschwerdt, Adam J. Birkenheuer, and Barbara A. QurolloComments to Author 
Author affiliation: North Carolina State University College of Veterinary Medicine, Raleigh, North Carolina, USA

Main Article

Figure 3

Microscopic images from study of isolation and characterization of Rickettsia finnyi, novel pathogenic spotted fever group Rickettsia in dogs, United States. Images depict R. finnyi sp. nov. strain 2024-CO-Wats–infected 030D canine mononuclear cells (A–C), DH82 canine histiocytic cells (D–F), and Vero E6 primate epithelial cells (G–I) detected by immunofluorescence using R. finnyi sp. nov.–seroreactive canine serum (dog 2, May 15 date from Table 2). Scale bar indicates 20 µm. SFGR nonreactive canine serum was used as a negative control. Green represents 2024-CO-Wats organisms. Blue represents nuclei of individual mammalian host cells (DAPI). SFGR, spotted fever group Rickettsia.

Figure 3. Microscopic images from study of isolation and characterization of Rickettsia finnyi, novel pathogenic spotted fever group Rickettsia in dogs, United States. Images depict R. finnyi sp. nov. strain 2024-CO-Wats–infected 030D canine mononuclear cells (A–C), DH82 canine histiocytic cells (D–F), and Vero E6 primate epithelial cells (G–I) detected by immunofluorescence using R. finnyi sp. nov.–seroreactive canine serum (dog 2, May 15 date from Table 2). Scale bar indicates 20 µm. SFGR nonreactive canine serum was used as a negative control. Green represents 2024-CO-Wats organisms. Blue represents nuclei of individual mammalian host cells (DAPI). SFGR, spotted fever group Rickettsia.

Main Article

1These authors contributed equally to this article.

Page created: September 24, 2025
Page updated: December 10, 2025
Page reviewed: December 10, 2025
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