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Volume 31, Number 2—February 2025
Research

Cyclospora Genotypic Variations and Associated Epidemiologic Characteristics, United States, 2018–2021

John Shen, Vitaliano A. Cama1, David Jacobson, Joel Barratt, and Anne Straily1Comments to Author 
Author affiliation: Oak Ridge Institute for Science and Education, Oak Ridge, Tennessee, USA (J. Shen); Centers for Disease Control and Prevention, Atlanta, Georgia, USA. (J. Shen, V.A. Cama, D. Jacobson, J. Barratt, A. Straily)

Main Article

Table 3

Patient-reported clinical symptoms and outcomes overall and by Cyclospora species exposure in study of Cyclospora genotypic variations and associated epidemiologic characteristics, United States, 2018–2021*

Clinical symptom or outcome Overall Infected with C. ashfordi Infected with C. cayetanensis p value
No. patients
 1,538
 437
 1,101
Diarrhea 0.92
Y 1,224 (98) 365 (98) 859 (98)
N 26 (2.1) 8 (2.1) 18 (2.1)
Missing, no.
 288
 64
 224
Weight loss 0.71
Y 856 (72) 255 (71) 601 (72)
N 340 (28) 105 (29) 235 (28)
Missing, no.
 342
 77
 265
Fever 0.71
Y 758 (63) 231 (64) 527 (63)
N 445 (37) 131 (36) 314 (37)
Missing, no.
 335
 75
 260
Fatigue 0.003
Y 920 (76) 257 (71) 663 (79)
N 283 (24) 105 (29) 178 (21)
Missing, no.
 335
 75
 260
Anorexia 0.86
Y 751 (63) 229 (63) 522 (63)
N 440 (37) 132 (37) 308 (37)
Missing, no.
 347
 76
 271
Nausea 0.076
Y 829 (69) 236 (65) 593 (70)
N 379 (31) 127 (35) 252 (30)
Missing, no.
 330
 74
 256
Vomiting 0.14
Y 823 (68) 258 (71) 565 (67)
N 380 (32) 103 (29) 277 (33)
Missing, no. 335 76 259

*Values are no. (%) except as indicated.

Main Article

1These senior authors were co–principal investigators.

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Page updated: January 22, 2025
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