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Volume 31, Number 2—February 2025
Dispatch
Infection by Tickborne Bacterium Candidatus Midichloria Associated with First Trimester Pregnancy Loss, Tennessee, USA
John Newman, Caitlin Hughes, Karen C. Bloch, Khalil J. Deveaux, Scott Allen, Thao T. Truong, Behzad Najafian, Abelardo C. Moncayo, Lili Tao, Joshua Lieberman, and Hernán Correa
Table
Laboratory testing at initial and follow-up evaluations in study of Infection by tickborne bacterium Candidatus Midichloria associated with first trimester pregnancy loss, Tennessee, USA*
| Laboratory study | Acute testing, 2023 Apr 30, 2 weeks after tick bite | Convalescent testing, 2023 Jun 19, 11 weeks after tick bite |
|---|---|---|
| Complete blood count | ||
| Leukocyte count, × 103 cells/μL | 7.4 | 7.8 |
| Platelets, × 103/μL |
227 |
221 |
| Liver function tests | ||
| Alanine transaminase, U/L | Not evaluated | 23 |
| Aspartate transaminase, U/L | Not evaluated | 24 |
| Total bilirubin, mg/dL | Not evaluated | 0.5 |
| Alkaline phosphatase, U/L |
Not evaluated |
54 |
| Serologic testing | ||
| Borrelia burgdorferi Western blot | ||
| IgM | 0/3 bands | 0/3 bands |
| IgG | 2/10 bands | 2/10 bands |
| Ehrlichia chaffensis EIA | ||
| IgM | <1:16 | <1:16 |
| IgG | <1:64 | <1:64 |
| Spotted fever group Rickettsia EIA | ||
| IgM | <1:16 | <1:16 |
| IgG |
<1:64 |
<1:64 |
| Routine prenatal infectious disease panel | ||
| Chlamydia trachomatis, Neisseria gonorrhoeae, Treponema pallidum, HIV, hepatitis B virus, and hepatitis C virus |
Negative |
Not evaluated |
| Autoimmune panel | ||
| Antinuclear antibody survey | Not evaluated | Positive 1:320, smooth pattern |
| SSA (Ro) IgG Qual | Not evaluated | Negative |
| SSA (La) IgG Qual | Not evaluated | Negative |
| Scl-70 IgG Qual | Not evaluated | Negative |
| Smith (Sm) IgG Qual | Not evaluated | Negative |
| RNP Ab Calc | Not evaluated | Negative |
| Anti-dsDNA | Not evaluated | Negative |
*Anti-dsDNA, anti-double stranded DNA; EIA, enzyme immunoassay; RNP Ab Calc, antiribonucleoprotein antibody calculation; Scl-70 IgG Qual, scleroderma antibody qualitative.
Page created: December 06, 2024
Page updated: January 16, 2025
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