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Model-Based Analysis of Impact, Costs, and Cost-Effectiveness of Tuberculosis Outbreak Investigations, United States
Sourya Shrestha
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, Lucia Cilloni, Garrett R. Beeler Asay, J. Steve Kammerer, Kala Raz, Tambi Shaw, Martin Cilnis, Jonathan Wortham, Suzanne M. Marks, and David Dowdy
Author affiliation: Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA (S. Shrestha, L. Cilloni, D. Dowdy); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (G.R.B. Asay, J.S. Kammerer, K. Raz, J. Wortham, S.M. Marks); California Department of Public Health, Richmond, California, USA (T. Shaw, M. Cilnis)
Main Article
Figure 1

Figure 1. Projected TB cases and outbreaks, 2023–2032, United States, in study of impact, costs, and cost-effectiveness of TB outbreak investigations. Shown are the total number of TB cases (A), the number of TB cases occurring in outbreaks (B), the total number of TB clusters (C), and the number of TB outbreaks (i.e., clusters of >3 cases) (D) projected to occur during 2023–2032 and cluster size distributions of the TB clusters (E). Clusters of size 1 are assumed to have no transmission links, and only clusters with >3 cases (shaded in orange) are investigated in outbreak investigations.
Main Article
Page created: January 17, 2025
Page updated: February 21, 2025
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