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Volume 31, Number 5—May 2025
Research

Metagenomic Identification of Fusarium solani Strain as Cause of US Fungal Meningitis Outbreak Associated with Surgical Procedures in Mexico, 2023

Charles Y. ChiuComments to Author , Venice Servellita, Mikael de Lorenzi-Tognon, Patrick Benoit, Nanami Sumimoto, Abiodun Foresythe, Filipe M. Cerqueira, Natalie Williams-Bouyer, Ping Ren, Lauren Nicholas S. Herrera, David C. Gaston, Leanna Sayyad, Shannon L. Whitmer, John Klena, Holenarasipur R. Vikram, Jeremy A.W. Gold, Lalitha Gade, Lindsay Parnell, Elizabeth Misas, Tom M. Chiller, Isabel S. Griffin, Sridhar V. Basavaraju, Dallas J. Smith, Anastasia P. Litvintseva, and Nancy A. Chow
Author affiliation: Chan-Zuckerberg Biohub, San Francisco, California, USA (C.Y. Chiu); University of California San Francisco, San Francisco, California, USA (C.Y. Chiu, V. Servellita, M. de Lorenzi-Tognon, P. Benoit, N. Sumimoto, A. Foresythe); Abbott Pandemic Defense Coalition, Abbott Park, Illinois, USA (C.Y. Chiu, V. Servellita, M. de Lorenzi-Tognon, P. Benoit, N. Sumimoto, A. Foresythe); The University of Texas Medical Branch at Galveston, Galveston, Texas, USA (F.M. Cerqueira, N. Williams-Bouyer, P. Ren); Vanderbilt University Medical Center, Nashville, Tennessee, USA (L.N.S. Herrera, D.C. Gaston); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (L. Sayyad, S.L. Whitmer, J. Klena, J.A.W. Gold, L. Gade, L. Parnell, E. Misas, T.M. Chiller, I.S. Griffin, S.V. Basavaraju, D.J. Smith, A.P. Litvintseva, N.A. Chow); Mayo Clinic, Phoenix, Arizona, USA (H.R. Vikram)

Main Article

Table 2

Data from de novo assembly of 18 draft genomes used for identification of Fusarium solani strain as cause of fungal meningitis US outbreak associated with surgical procedures in Mexico, 2023*

Genome assembly No. contigs Total contig length, bp N50, bp
B10740 2,589 50,517,664 489,689
B10927 3,421 49,206,550 371,903
B10983 3,198 57,260,205 506,490
B15100 2,250 49,683,915 842,580
B17986 3,037 47,958,675 381,199
B18090 5,155 60,209,829 470,869
B18091 6,769 59,741,266 458,563
B18313 1,448 51,560,784 467,209
B18339 2,419 55,485,754 565,856
B18386 1,781 52,521,438 575,687
B18421 7,187 59,392,883 357,605
B18478 7,244 56,253,777 441,893
B18854 2,695 54,697,765 562,797
B21339 2,532 55,305,429 898,025
B22247 2,284 56,659,172 747,616
B22248 1,071 51,606,190 538,696
B27166 2,186 53,744,553 512,232
B27264 2,262 54,164,081 802,132

*bp, base pairs; N50, shortest contig length that needs to be included to cover 50% of the genome.

Main Article

Page created: March 21, 2025
Page updated: April 03, 2025
Page reviewed: April 03, 2025
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