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Volume 32, Number 1—January 2026

Research

Reduced Emergency Department Visits and Hospitalizations in Infants after Universal Respiratory Syncytial Virus Immunization, Italy, 2024–25

Simone Villa1Comments to Author , Simona Scarioni1, Enrico Pigozzi, Manuel Maffeo, Mauro Maistrello, Giorgio Bagarella, Francesco Scovenna, Federica Morani, Marlen Romano, Gianvincenzo Zuccotti, Massimo Agosti, Catia Borriello, Elena Pariani, Guido Bertolaso, Luigi Vezzosi, Fausto Baldanti, Mario Melazzini, Elena Azzolini, Gabriele del Castillo2, Danilo Cereda2, and Regional Immunization Council3
Author affiliation: Directorate General for Health, Lombardy Region, Milan, Italy (S. Villa, S. Scarioni, E. Pigozzi, M. Maffeo, M. Maistrello, G. Bagarella, F. Scovenna, F. Morani, C. Borriello, G. Bertolaso, L. Vezzosi, M. Melazzini, G. del Castillo, D. Cereda); University of Milan, Milan (S. Villa, S. Scarioni, E. Pigozzi, F. Scovenna, G. Zuccotti, E. Pariani); Regional Company for Innovation and Purchasing Aria S.p.A., Milan (M. Romano); Buzzi Children’s Hospital, Milan (G. Zuccotti); Hospital “F. Del Ponte,” University of Insubria, Varese, Italy (M. Agosti); Fondazione IRCCS Policlinico San Matteo, Pavia, Italy (F. Baldanti); University of Pavia, Pavia (F. Baldanti); Humanitas University, Pieve Emanuele, Italy (E. Azzolini)

Main Article

Table 1

EDVs and hospitalizations for lower respiratory tract infection at seasonal peak week among children in study of reduced EDVs and hospitalizations in infants after universal respiratory syncytial virus immunization, Italy, 2024–25*

Winter season Children <12 mo
 Children 1–5 y
EDVs Hospital admission EDVs Hospital admission
2018–19 221 (week 1) 176 (week 1) 13 (week 5) 9 (week 50)
2019–20 230 (week 52) 175 (week 1) 33 (week 52) 10 (week 9)
2020–21 10 (week 41) 13 (week 42) 5 (week 40) 3 (week 41)
2021–22 354 (week 46) 268 (week 46) 37 (week 46) 16 (week 45)
2022–23 358 (week 1) 250 (week 49) 24 (week 49) 24 (week 52)
2023–24 364 (week 52) 212 (week 52) 35 (week 51) 24 (week 51)
2024–25 123 (week 52) 73 (week 1) 43 (week 52) 18 (week 6)

*Numbers shown are for winter seasons from 2018–19 to 2024–25. The ISO week in which the peak was reached is indicated in parentheses. EDV, emergency department visit.

Main Article

1These authors contributed equally to this article and share first authorship.

2These authors contributed equally to this article and share last authorship.

3Members of the Regional Immunization Council are listed at the end of this article.

Page created: December 13, 2025
Page updated: January 29, 2026
Page reviewed: January 29, 2026
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