Emergence of New Delhi Metallo-β-Lactamase 14–Producing Klebsiella pneumoniae Sequence Type 147 Clone in Spain and Outbreak in the Canary Islands
Pablo Aja-Macaya
1, Tania Blanco-Martín
1, Cristian Mateo-León
1, Cristóbal del Rosario-Quintana, Carmen Piña, Enrique de la Cruz-Tabares, Salud Rodríguez-Pallares, Lucía González-Pinto, Alejandro Beceiro, Marina Oviaño, Germán Bou, Diego García-Martínez de Artola
2, and Jorge Arca-Suárez
2
Author affiliation: Servicio de Microbiología Clínica and Instituto de Investigación Biomédica A Coruña (INIBIC), Complexo Hospitalario Universitario, A Coruña, Spain (P. Aja-Macaya, T. Blanco-Martín, S. Rodríguez-Pallares, L. González-Pinto, A. Beceiro, M. Oviaño, G. Bou, J. Arca-Suárez); CIBER de Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, Madrid, Spain (T. Blanco-Martín, A. Beceiro, M. Oviaño, G. Bou, J. Arca-Suárez); Hospital Universitario Nuestra Señora de la Candelaria, Santa Cruz de Tenerife, Spain (C. Mateo-León, D. García-Martínez de Artola); Complejo Hospitalario Universitario Insular-Materno Infantil de Gran Canaria, Las Palmas de Gran Canaria, Spain (C. del Rosario-Quintana, C. Piña); Complejo Hospitalario Universitario Insular-Materno Infantil de Gran Canaria, Las Palmas de Gran Canaria (Enrique de la Cruz-Tabares)
Main Article
Figure 2
Figure 2. Core-genome phylogenomic tree of New Delhi metallo-β-lactamase (NDM) 14–producing Klebsiella pneumoniae ST147 isolates from a Canary Islands outbreak and related isolates from study of emergence of NDM-14–producing K. pneumoniae ST147 clone in Spain and outbreak in the Canary Islands. The tree includes the closest 863 genomes of K. pneumoniae isolates belonging to the ST147 clone, found in PasteurMLST (https://bigsdb.pasteur.fr/klebsiella), the National Center for Biotechnology Information Genome Database (https://www.ncbi.nlm.nih.gov/genome), and Pathogenwatch (https://pathogen.watch). Red shading indicates the Canary Island outbreak isolates; other countries and STs of interest are also highlighted. The most prevalent carbapenemases appearing in the dataset of the most similar isolates are noted. K. pneumoniae isolate TGH13 (GenBank accession no. CP012745.1) was used as the reference strain. Scale bar indicates nucleotide substitutions per site. cgST, core-genome ST; ST, sequence type.
Main Article
Page created: December 04, 2025
Page updated: January 29, 2026
Page reviewed: January 29, 2026
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.