Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link

Volume 32, Number 1—January 2026

Research

Emergence of New Delhi Metallo-β-Lactamase 14–Producing Klebsiella pneumoniae Sequence Type 147 Clone in Spain and Outbreak in the Canary Islands

Pablo Aja-Macaya1, Tania Blanco-Martín1, Cristian Mateo-León1, Cristóbal del Rosario-Quintana, Carmen Piña, Enrique de la Cruz-Tabares, Salud Rodríguez-Pallares, Lucía González-Pinto, Alejandro Beceiro, Marina Oviaño, Germán Bou, Diego García-Martínez de Artola2, and Jorge Arca-Suárez2Comments to Author 
Author affiliation: Servicio de Microbiología Clínica and Instituto de Investigación Biomédica A Coruña (INIBIC), Complexo Hospitalario Universitario, A Coruña, Spain (P. Aja-Macaya, T. Blanco-Martín, S. Rodríguez-Pallares, L. González-Pinto, A. Beceiro, M. Oviaño, G. Bou, J. Arca-Suárez); CIBER de Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, Madrid, Spain (T. Blanco-Martín, A. Beceiro, M. Oviaño, G. Bou, J. Arca-Suárez); Hospital Universitario Nuestra Señora de la Candelaria, Santa Cruz de Tenerife, Spain (C. Mateo-León, D. García-Martínez de Artola); Complejo Hospitalario Universitario Insular-Materno Infantil de Gran Canaria, Las Palmas de Gran Canaria, Spain (C. del Rosario-Quintana, C. Piña); Complejo Hospitalario Universitario Insular-Materno Infantil de Gran Canaria, Las Palmas de Gran Canaria (Enrique de la Cruz-Tabares)

Main Article

Figure 4

Detailed comparison of circularized blaNDM-14 plasmids from study of emergence of New Delhi metallo-β-lactamase (NDM) 14–producing Klebsiella pneumoniae ST147 clone in Spain and outbreak in the Canary Islands. Plasmids are from multiple countries (Spain, I238 and I542; France, 296B5; United Kingdom, KP88) and 2 different STs. Gray lines indicate synteny at the nucleotide level. Gray shading indicates loci without gene names or named hypothetical proteins; other colors are randomized on the basis of gene order. bleMBL, bleomycin resistance gene; CTX, cholera toxin; IS, insertion sequence; ORF, open reading frame; OXA, oxacillin; pNDM-14, NDM-14–producing plasmid; ST, sequence type.

Figure 4. Detailed comparison of circularized blaNDM-14 plasmids from study of emergence of New Delhi metallo-β-lactamase (NDM) 14–producing Klebsiella pneumoniae ST147 clone in Spain and outbreak in the Canary Islands. Plasmids are from multiple countries (Spain, I238 and I542; France, 296B5; United Kingdom, KP88) and 2 different STs. Gray lines indicate synteny at the nucleotide level. Gray shading indicates loci without gene names or named hypothetical proteins; other colors are randomized on the basis of gene order. bleMBL, bleomycin resistance gene; CTX, cholera toxin; IS, insertion sequence; ORF, open reading frame; OXA, oxacillin; pNDM-14, NDM-14–producing plasmid; ST, sequence type.

Main Article

1These first authors contributed equally to this article.

2These senior authors contributed equally to this article.

Page created: December 04, 2025
Page updated: January 29, 2026
Page reviewed: January 29, 2026
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external