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Volume 32, Number 3—March 2026

Research

Lymphocytic Choriomeningitis Virus Seroprevalence among Urban Pregnant Women and Newborns, Philadelphia, Pennsylvania, USA, 2021

Dustin D. Flannery1Comments to Author , Caitlin M. Cossaboom1, Timothy D. Flietstra, Alvaro Zevallos Barboza, Heather H. Burris, Karen M. Puopolo, Aridth Gibbons, Deborah L. Cannon, Inna Krapiunaya, Leanna Sayyad, Katrin S. Sadigh, Kami Smith, Joel M. Montgomery, Trevor Shoemaker, John D. Klena, and Scott M. Gordon
Author affiliation: Author affiliations: Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA (D.D. Flannery, A. Zevallos Barboza, H.H, Burris, K.M. Puopolo, S.M. Gordon); University of Pennsylvania Perelman School of Medicine, Philadelphia (D.D. Flannery, H.H. Burris, K.M. Puopolo, S.M. Gordon); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (C.M. Cossaboom, T.D. Flietsra, A. Gibbons, D.L. Cannon, I. Krapiunaya, L. Sayyad, K.S. Sadigh, K. Smith, J.M. Montgomery, T. Shoemaker, J.D. Klena)

Main Article

Table 1

Phase-specific lymphocytic choriomeningitis virus seroprevalence among urban pregnant women, Philadelphia, Pennsylvania, USA*

Analysis phase No. (%) seropositive
Pregnant women, n = 1,000 25 (2.5)
Phase 1, n = 700 17 (2.4)
Phase 2, n = 300
 8 (2.7)
Pregnant women with antenatally diagnosed fetal brain anomaly; phase 3, n = 37 0

*Maternal lymphocytic choriomeningitis virus (LCMV) seroprevalence detected by LCMV IgG during pregnancy. For phases 1 and 2, neighborhood deprivation at the census tract level calculated by using the Community Deprivation Index (17,18). Scores are divided into 4 quartiles from least deprived (Q1) to most deprived (Q4). Scores are as follows: Q1 is <0.324; Q2 is 0.324–0.449; Q3 is 0.45–0.579; and Q4 is >0.58. Phase 1 included persons residing in the highest quartile of neighborhood deprivation; phase 2, included residents of all 4 quartiles of neighborhood deprivation. Phase 3 included persons with fetal brain anomalies diagnosed antenatally.

Main Article

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1These first authors contributed equally to this article.

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