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Volume 32, Number 3—March 2026

Research

Environmental and Phylogenetic Investigations of Aspergillus flavus Outbreak Linked to Contaminated Building Materials, Denmark, 2025

Alexander Gewecke, Raphael Niklaus Sieber, Søren Hallstrøm, Marc Stegger, Barbara Kolarik, Jenny D. Knudsen, Birgitte Andersen, Astrid Hall, Nadja Hawwa Vissing, and Maiken Cavling ArendrupComments to Author 
Author affiliation: Statens Serum Institut, Copenhagen, Denmark (A. Gewecke, R.N. Sieber, S. Hallstrøm, M. Stegger, M.C. Arendrup); Harry Butler Institute, Murdoch University, Perth, Western Australia, Australia (M. Stegger); dansk MiljøAnalyse, Vedbæk, Denmark (B. Kolarik); Copenhagen University Hospital, Rigshospitalet, Copenhagen (J.D. Knudsen, A. Hall, N.H. Vissing, M.C. Arendrup); Aalborg University, Copenhagen (B. Andersen); University of Copenhagen, Copenhagen (M.C. Arendrup)

Main Article

Figure 5

Rooted maximum-likelihood phylogeny of 167 A. flavus isolates (cropped) from study of environmental and phylogenetic investigations of A. flavus outbreak linked to contaminated building materials, Denmark, 2025. The tree shows clear distinction of several major clusters, including 1 monophyletic cluster 10 that contained all outbreak isolates. The tree was reconstructed based on 303,560 core-genome SNPs and rooted with MUS_9860 as outgroup. Scale bar indicates substitutions per site. Clusters were determined using TreeCluster (https://github.com/niemasd/TreeCluster). Full tree available in Appendix 1. BAL, bronchoalveolar lavage; NA, not available (information on material source); RH, Rigshospitalet; SNP, single-nucleotide polymorphism.

Figure 5. Rooted maximum-likelihood phylogeny of 167 A. flavus isolates (cropped) from study of environmental and phylogenetic investigations of A. flavus outbreak linked to contaminated building materials, Denmark, 2025. The tree shows clear distinction of several major clusters, including 1 monophyletic cluster 10 that contained all outbreak isolates. The tree was reconstructed based on 303,560 core-genome SNPs and rooted with MUS_9860 as outgroup. Scale bar indicates substitutions per site. Clusters were determined using TreeCluster (https://github.com/niemasd/TreeCluster). Full tree available in Appendix 1. BAL, bronchoalveolar lavage; NA, not available (information on material source); RH, Rigshospitalet; SNP, single-nucleotide polymorphism.

Main Article

Page created: January 21, 2026
Page updated: March 20, 2026
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