Volume 32, Number 3—March 2026
Research
Environmental and Phylogenetic Investigations of Aspergillus flavus Outbreak Linked to Contaminated Building Materials, Denmark, 2025
Table 2
Aspergillus flavus genotypes found in 145 isolates in study of environmental and phylogenetic investigations of Aspergillus flavus outbreak linked to contaminated building materials, Denmark, 2025*
| Source of isolate(s) (genotype) | No. isolates | STRAfla-markers |
Comments | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 2A | 2B | 2C | 3A | 3B | 3C | 4A | 4B | 4C | |||
| Patients 1, 2, 4, 6, 9, 10, 16, 17, 18, 20, 21 (genotype A)† | 19 | 26 | 11 | 12 | 12 | 26 | 9 | 9 | 5 | 9 | |
| Patient 21 | 3 | 26 | 11 | 12 | 12 | 25 | 9 | 9 | 5 | 9 | |
| Patients 5, 7 ,12–14, 15, 19 (genotype B) | 8 | 25 | 11 | 12 | 12 | 26 | 9 | 9 | 5 | 9 | |
| Patient 11 | 1 | 26 | 11 | 12 | 12 | 27 | 9 | 9 | 5 | 9 | |
| Patient 11 | 1 | 27 | 11 | 12 | 12 | 27 | 9 | 9 | 5 | 9 | |
| Patient 8 | 1 | 26 | 11 | 14 | 12 | 26 | 9 | 9 | 5 | 9 | |
| Patient 3 | 1 | 25 | 11 | 12 | 12 | 26 | 9 | 9 | 5 | NA‡ | |
| Patient 15 |
1 |
25 |
11 |
12 |
12 |
26 |
13 |
9 |
5 |
9 |
|
| Air samples (genotype A)† | 9 | 26 | 11 | 12 | 12 | 26 | 9 | 9 | 5 | 9 | Pediatric hematology ward |
| Plywood cupboard in room A§ (genotype A)† | 2 | 26 | 11 | 12 | 12 | 26 | 9 | 9 | 5 | 9 | Pediatric hematology ward |
| Vacuum cleaner bag (genotype A)† | 2 | 26 | 11 | 12 | 12 | 26 | 9 | 9 | 5 | 9 | Pediatric hematology ward |
| DCM laboratory incubator (genotype B) |
5 |
25 |
11 |
12 |
12 |
26 |
9 |
9 |
5 |
9 |
|
| Hospital interior (genotype A)† | 69 | 26 | 11 | 12 | 12 | 26 | 9 | 9 | 5 | 9 | Adult/pediatric hematology ward |
| Hospital interior | 1 | 62 | 11 | 12 | 9 | 20 | 9 | 7 | 12 | 10 | Central complex |
| Hospital interior | 1 | 40 | 12 | 11 | 8 | 13 | 4 | 7 | 7 | 9 | South complex¶ |
| Hospital interior | 1 | 31 | 11 | 10 | 8 | 13 | 14 | 7 | 12 | 10 | Adult hematology ward |
| Hospital interior | 2 | 27 | 13 | 8 | 14 | 29 | 9 | 9 | 5 | 9 | Central complex |
| Hospital interior | 1 | 20 | 16 | 11 | 10 | 22 | 32 | 7 | 8 | 8 | Pediatric hematology ward |
| Hospital interior | 2 | 15 | 16 | 28 | 11 | 17 | 15 | 7 | 8 | 9 | South complex¶ |
| Hospital interior |
1 |
14 |
11 |
10 |
8 |
22 |
9 |
7 |
12 |
10 |
Adult hematology ward |
| MDF (genotype C) | 1 | 26 | 11 | 13 | 12 | 28 | 9 | 9 | 5 | 9 | Retailer 1 |
| MDF (genotype D) | 1 | NA‡ | NA‡ | NA‡ | 12 | 27 | 9 | 9 | 5 | 9 | Retailer 2 |
| OSB (genotype E) | 1 | 26 | 11 | 12 | 12 | 27 | 9 | 9 | 5 | 9 | Retailer 1 |
| PW (genotype E) |
1 |
26 |
11 |
12 |
12 |
27 |
9 |
9 |
5 |
9 |
Retailer 1 |
| Soil-1a | 1 | 15 | 7 | 22 | 16 | 12 | 16 | 9 | 5 | 8 | |
| Soil-1b | 1 | 15 | 7 | 23 | 17 | 13 | 5 | 9 | 5 | 8 | |
| Soil-6a | 1 | 15 | 11 | 12 | 8 | 30 | 14 | 8 | 7 | 10 | |
| Soil-7a | 1 | 16 | 7 | 11 | 19 | 6 | 5 | 7 | 5 | 8 | |
| Soil-7b | 1 | 30 | 11 | 11 | 8 | 24 | 15 | 7 | 7 | 10 | |
| Soil-7c | 1 | 15 | 7 | 21 | 18 | 12 | 11 | 10 | 5 | 8 | |
| Soil-7d | 1 | 28 | 11 | 11 | 8 | 20 | 9 | 7 | 12 | 10 | |
| Soil-7e | 1 | 29 | 11 | 11 | 8 | 23 | 15 | 7 | 7 | 10 | |
| Soil-7f | 1 | 16 | 7 | 33 | 14 | 6 | 11 | 17 | 5 | 8 | |
| Soil-7g |
1 |
39 |
11 |
10 |
8 |
45 |
9 |
7 |
12 |
10 |
|
| Total | 145 | ||||||||||
*Including 33 isolates compiled from Gewecke et al. (6). Patient numbers in bold indicate cases in which culture-plate contamination was assumed because of lack of symptoms, lack of statements in the medical records, or both. Gray shading indicates STRAfla marker overlaps with outbreak. MDF, medium-density fiberboard; OSB, oriented strand board; PW, plywood. †Principal South complex outbreak cluster genotype A. ‡No STRAfla profile. §Microscopy-confirmed growth of A. flavus on kitchen plywood cupboard in room A (see Figure 4). ¶South complex but different floor than outbreak ward.