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Volume 32, Number 5—May 2026
Research
Updated Genomic Epidemiologic Description of Candida (Candidozyma) auris, United States
Lindsay A. Parnell
, Amanda Ribeiro Dos Santos, Kaitlin Forsberg, Meghan Lyman, Elizabeth Misas, Lalitha Gade, D. Joseph Sexton, Anastasia P. Litvintseva, and Nancy A. Chow
, Amanda Ribeiro Dos Santos, Kaitlin Forsberg, Meghan Lyman, Elizabeth Misas, Lalitha Gade, D. Joseph Sexton, Anastasia P. Litvintseva, and Nancy A. Chow
Table
Patient demographic data and clinical information for isolates sequenced in study of genomic epidemiologic description of Candida (Candidozyma) auris, United States
| Characteristic | No. (%) cases |
|||||||
|---|---|---|---|---|---|---|---|---|
| All, n = 1,535 | Central, n = 9 | Mid-Atlantic, n = 188 | Midwest, n = 234 | Mountain, n = 87 | Northeast, n = 560 | Southeast, n = 181 | West, n = 276 | |
| Case type | ||||||||
| Clinical | 736 (48) | 8 (89) | 55 (29) | 101 (43) | 29 (33) | 250 (45) | 156 (86) | 137 (50) |
| Screening* | 728 (47) | 1 (11) | 120 (64) | 132 (56) | 58 (67) | 266 (48) | 16 (9) | 135 (49) |
| Unknown |
71 (5) |
0 |
13 (7) |
1 (0.43) |
0 |
44 (8) |
9 (5) |
4 (1) |
| Specimen type | ||||||||
| Colonization screening sites | 727 (47) | 1 (11) | 120 (64) | 132 (56) | 58 (67) | 265 (47) | 16 (9) | 135 (49) |
| Blood | 293 (19) | 3 (33) | 18 (10) | 34 (15) | 13 (15) | 94 (17) | 70 (39) | 61 (22) |
| Ear | 9 (1) | 1 (11) | 0 | 1 (0.43) | 0 | 5 (1)* | 1 (1) | 1 |
| Fluid and drainage | 20 (1) | 0 | 3 (2) | 3 (1) | 0 | 9 (2) | 1 (1) | 4 (1) |
| Indwelling device | 10 (1) | 0 | 0 | 4 (2) | 0 | 3 (1) | 0 | 3 (1) |
| Respiratory | 80 (5) | 0 | 4 (2) | 8 (3) | 5 (6) | 28 (5) | 24 (13) | 11 (4) |
| Urine | 210 (14) | 2 (22) | 21 (11) | 35 (15) | 8 (9) | 75 (13) | 34 (19) | 35 (13) |
| Wound | 55 (4) | 0 | 8 (4) | 7 (3) | 2 (2) | 16 (3) | 17 (9) | 5 (2) |
| Other | 89 (6) | 2 (22) | 1 (1) | 9 (4) | 1 (1) | 48 (9) | 9 (5) | 19 (7) |
| Unknown |
42 (3) |
0 |
13 (7) |
1 (0.43) |
0 |
17 (3) |
9 (5) |
2 (1) |
| Age, y | ||||||||
| <21 | 10 (1) | 0 | 1 (1) | 1 (0.43) | 0 | 2 | 2 (1) | 4 (1) |
| >21 to <64 | 629 (41) | 5 (56) | 97 (52) | 127 (54) | 46 (53) | 183 (33) | 70 (39) | 101 (37) |
| >65 | 793 (52) | 2 (22) | 78 (41) | 83 (35) | 41 (47) | 316 (56) | 104 (57) | 169 (61) |
| Unknown |
103 (7) |
2 (22) |
12 (6) |
23 (10) |
0 |
59 (11) |
5 (3) |
2 (1) |
| Sex | ||||||||
| F | 519 (34) | 0 | 72 (38) | 72 (31) | 31 (36) | 199 (36) | 54 (30) | 91 (33) |
| M | 687 (45) | 7 (78) | 87 (46) | 100 (43) | 42 (48) | 255 (46) | 63 (35) | 133 (48) |
| Unknown |
329 (21) |
2 (22) |
29 (15) |
62 (26) |
14 (16) |
106 (19) |
64 (35) |
52 (19) |
| Year of collection | ||||||||
| 2013 | 1 (0.07) | 0 | 0 | 0 | 0 | 1 (0.18) | 0 | 0 |
| 2014 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 2015 | 1 (0.07) | 0 | 0 | 0 | 0 | 1 (0.18) | 0 | 0 |
| 2016 | 100 (7) | 0 | 6 (3) | 22 (9) | 0 | 72 (13) | 0 | 0 |
| 2017 | 350 (23) | 2 (22) | 3 (2) | 22 (9) | 0 | 317 (57) | 5 (3) | 1 (0.36) |
| 2018 | 123 (8) | 1 (11) | 3 (2) | 54 (23) | 1 (1) | 59 (11) | 4 (2) | 1 (0.36) |
| 2019 | 134 (9) | 1 (11) | 21 (11) | 5 (2) | 8 (9) | 7 (1) | 39 (22) | 53 (19) |
| 2020 | 295 (19) | 2 (22) | 61 (32) | 32 (14) | 2 (2) | 17 (3) | 84 (46) | 97 (35) |
| 2021 | 386 (25) | 2 (22) | 93 (49) | 82 (35) | 62 (71) | 37 (7) | 43 (24) | 67 (24) |
| 2022 | 145 (9) | 1 (11) | 1 (1) | 17 (7) | 14 (16) | 49 (9) | 6 (3) | 57 (21) |
*One early ear case in the Northeast was counted as a screening case because of circumstances of collection and case definition at the time.
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Page updated: April 23, 2026
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