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Volume 32, Number 7—July 2026

Research

National Surveillance of Enterovirus D68 Upsurge, France, 2024

Marion Jeannoël, Maxime Bisseux, Stéphanie Dan, Elisa Creuzet, Delphine Parraud, Jean-Luc Bailly, Jérémie Lebeurre, Amélie Brebion, Hélène Chabrolles, Laurence Josset, Cécile Henquell, Isabelle Schuffenecker, Audrey MirandComments to Author , and Enterovirus Surveillance Network1
Author affiliation: Hospices Civils de Lyon, Centre National de Référence des Entérovirus–Laboratoire Associé, Lyon, France (M. Jeannoël, S. Dan, D. Parraud, J. Lebeurre, L. Josset, I. Schuffenecker); Université Clermont Auvergne, Clermont-Ferrand (M. Bisseux, E. Creuzet, H. Chabrolles, C. Henquell, A. Mirand); Centre Hospitalier Universitaire de Clermont-Ferrand, Centre National de Référence des Entérovirus–Laboratoire Coordonnateur, Clermont-Ferrand, France (M. Bisseux, A. Brebion, H. Chabrolles, A. Mirand); Université Claude Bernard Lyon 1, Villeurbanne, France (S. Dan, D. Parraud, L. Josset); Université Clermont Auvergne, Clermont-Ferrand (J. Bailly)

Main Article

Figure 6

Amino acid change analysis of enterovirus D68, subgenotype B3, from report on national surveillance of enterovirus D68 upsurge, France, 2021–2024. Amino acid substitutions leading to changes in the predominant residues between B3-II (n = 61 sequences) and the monophyletic clade corresponding to the nearest common ancestor B3-I (n = 106 sequences) are shown. Mutation positions are numbered according to the reference Fermon strain (GenBank accession no. AY426531) and annotated by the corresponding nonstructural viral proteins (3A and 3D). For each of the positions showing a mutation in the new group, the frequency of each amino acid was visualized using WebLogo (https://weblogo.threeplusone.com). A, alanine; I, isoleucine; T, threonine; Y, tyrosine; V, valine.

Figure 6. Amino acid change analysis of enterovirus D68, subgenotype B3, from report on national surveillance of enterovirus D68 upsurge, France, 2021–2024. Amino acid substitutions leading to changes in the predominant residues between B3-II (n = 61 sequences) and the monophyletic clade corresponding to the nearest common ancestor B3-I (n = 106 sequences) are shown. Mutation positions are numbered according to the reference Fermon strain (GenBank accession no. AY426531) and annotated by the corresponding nonstructural viral proteins (3A and 3D). For each of the positions showing a mutation in the new group, the frequency of each amino acid was visualized using WebLogo (https://weblogo.threeplusone.com). A, alanine; I, isoleucine; T, threonine; Y, tyrosine; V, valine.

Main Article

1Additional members of Enterovirus Surveillance Network who contributed data are listed at the end of this article.

Page created: April 30, 2026
Page updated: June 04, 2026
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