Volume 32, Number 7—July 2026
Research
National Surveillance of Enterovirus D68 Upsurge, France, 2024
, and Enterovirus Surveillance Network1
Table 1
Patient characteristics and clinical outcomes in study of EV-D68 upsurge, France, 2024*
| Characteristic | Children 0–17 y, n = 363 | Adults |
||
|---|---|---|---|---|
| 18–64 y, n = 155 | >65 y, n = 134 | Total, n = 289 | ||
| Median age, y (IQR) | 2.0 (0.04–7) | 45 (34–56) | 76 (70–82) | 62 (43–75) |
| Female/male ratio | 0.76 | 0.49 | 0.55 | 1.08 |
| EV-D68 severe infections | 102/363 (28.1) | 38/155 (24.5) | 29/134 (21.6) | 67/289 (23.2) |
| Hospitalization† | 308/358 (86.0) | 126/150 (84.0) | 127/131 (96.9) | 253/281 (90.04) |
| Intensive care unit‡ | 85/343 (24.78) | 42/143 (29.4) | 27/125 (21.6) | 69/268 (25.75) |
| Death | 2/363 (0.6)§ | 3/155 (1.9) | 6/134 (4.5) | 9/289 (3.1)¶ |
*Values are no. (%) except as indicated. EV-D68, enterovirus D68; IQR, interquartile range. †Hospitalization requirement was reported for 358 children and 281 adults. ‡Intensive care requirement was reported for 343 children and 268 adults. §Sudden infant death syndrome. Although EV-D68 was the only detected pathogen, EV-D68 infection was considered as the possible cause of death; attributing causality can be challenging without thorough investigation in such contexts. ¶Among the 9 adults, the EV-D68 infection was considered as the probable cause of death in 4 patients (EV-D68 was the only detected pathogen) and as possible in 5 patients (evidence or strong suspicion of bacterial co-infection).
1Additional members of Enterovirus Surveillance Network who contributed data are listed at the end of this article.