Table 3

Transmission Routes for Nipah Virus from Malaysia and Bangladesh

Bronwyn A. Clayton, Deborah Middleton, Jemma Bergfeld, Jessica Haining, Rachel Arkinstall, Linfa Wang, and Glenn A. Marsh

Author affiliations: Author affiliations: Commonwealth Scientific and Industrial Research Organisation Livestock Industries, Geelong, Victoria, Australia (B.A. Clayton, D. Middleton, J. Bergfeld, J. Haining, R. Arkinstall, L. Wang, G.A. Marsh); University of Melbourne, Parkville, Victoria, Australia (B.A. Clayton); Duke–National University of Singapore Graduate Medical School, Singapore (L. Wang)

Main Article

Viral RNA and virus isolation results from ferrets experimentally infected with Nipah virus, Malaysia strain*

Dpi 1	Dpi 2	Dpi 3	Dpi 4	Dpi 5	Dpi 6	Dpi 7	Dpi 8	Dpi 9	Dpi 10
M9
NW	–		+/−		+/−‡		+/+
OS	–		+/+		–‡		+/−
RS	–		–		+/+‡		+/−
Blood	–		–		+/−‡		+/+
M10
NW	–		+/−		+/+‡		+/+
OS	–		–		–‡		+/+
RS	–		–		+/−‡		+/−
Blood	–		–		–‡		+/+
M11
NW	–		+/−		+/+
OS	–		–		+/−
RS	–		–		–
Blood	–		–		+/+
M12
NW		+/+		+/+‡		+/−		+/+
OS		–		–‡		Indet		+/−
RS		–		–‡		+/−		+/+
Blood		–		–‡		+/+		+/+
M13
NW		–		+/−		+/+‡		NS	+/+
OS		–		–		–‡		NS	+/+
RS		–		–		+/+‡		NS	+/−
Blood		–		–		–‡		NS	+/+
M14
NW		–		+/−		+/+‡		+/+
OS		–		–		+/−‡		+/+
RS		–		–		–‡		+/−
Blood		–		–		+/+‡		+/+
M15
NW		–		+/−		+/+		+/−‡		+/+
OS		–		–		+/−		–‡		+/+
RS		–		–		+/−		+/§		+/−
Blood		–		–		+/+		+/+‡		+/+

*Dpi, days postinfection; NW, nasal wash; –, Nipah virus not detected by reverse transcription PCR (RT-PCR) for N gene; therefore, virus isolation was not attempted for this sample; empty cells represent days on which sampling was not scheduled for that animal; +/−, virus detected by RT-PCR but negative by virus isolation; +/+, sample positive by RT-PCR and virus isolation; OS, oral sample; RS, rectal sample; Indet, mean cycle threshold value >39.1 (the defined cutoff value for positive samples); NS ,not sampled
†RNA detection by RT-PCR.
‡Pyrexia first detected.
§Virus isolation not attempted for this sample.

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Page created: November 20, 2012

Page updated: November 20, 2012

Page reviewed: November 20, 2012

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