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Volume 23, Number 4—April 2017
Dispatch

Significant Decrease in Pertactin-Deficient Bordetella pertussis Isolates, Japan

Yukihiro HiramatsuComments to Author , Yusuke Miyaji, Nao Otsuka, Yoshichika Arakawa, Keigo Shibayama, and Kazunari Kamachi
Author affiliations: National Institute of Infectious Diseases, Tokyo, Japan (Y. Hiramatsu, Y. Miyaji, N. Otsuka, K. Shibayama, K. Kamachi); St. Marianna University School of Medicine, Kawasaki, Japan (Y. Miyaji); Nagoya University Graduate School of Medicine, Nagoya, Japan (Y. Arakawa)

Main Article

Table

Molecular mechanisms of loss of pertactin production in 59 pertactin-deficient Bordetella pertussis isolates, Japan, 2005–2016*

Reason for loss of pertactin
 No. (%) MTs
MT27
 MT186
 Others†
ΔSS 0 43 (72.9) 11 (18.6)
1598–1599::IS481 0 2 (3.4) 1 (1.7)
245–246::IS481 1 (1.7) 0 0
Transcriptional downregulation
 1 (1.7)
 0
 0
Total 2 (3.4) 45 (76.3) 12 (20.3)

*MT, types determined by using multilocus variable-number tandem-repeat analysis.
†For convenience, minor MTs (MT194, MT224–226, and MT314–316) are included in this category.

Main Article

Page created: March 16, 2017
Page updated: March 16, 2017
Page reviewed: March 16, 2017
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