Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

Volume 23, Number 6—June 2017

Research

Invasive Serotype 35B Pneumococci Including an Expanding Serotype Switch Lineage, United States, 2015–2016

Sopio Chochua, Benjamin J. Metcalf, Zhongya Li, Hollis Walker, Theresa Tran, Lesley McGee, and Bernard BeallComments to Author 
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA

Main Article

Table 3

Annual incidence and proportions of penicillin-nonsusceptible 35B pneumococcal isolates causing IPD, United States, 1999–2015*

Year Surveillance population % CIS No. 35B isolates from patients by age, y
Relative incidence of 35B IPD† Pen MIC, μg/mL
penNS 35B isolates/penS 35B isolates
<5 ≥5 >2 0.12−1 <0.06
1998 17,383,935 86.1 3 18 1.40 9 5 7 2.0
1999 18,550,681 87.0 2 18 1.24 8 3 9 1.2
2000 19,821,607 86.3 4 21 1.46 7 9 9 1.8
2001 22,479,308 88.1 2 40 2.12 14 18 10 3.2
2002 25,051,246 87.6 2 34 1.64 20 8 8 3.5
2003 25,264,246 91.4 11 49 2.56 22 26 11 4.4
2004 27,419,898 87.9 15 69 3.49 44 25 15 4.6
2005 27,816,784 89.5 11 57 2.73 35 18 15 3.5
2006 28,204,455 86.7 1 65 2.70 37 15 14 3.7
2007 28,579,312 87.5 5 83 3.52 51 23 14 5.3
2008 28,856,774 86.7 12 80 3.68 62 16 14 5.6
2009 29,206,528 89.8 8 70 2.97 45 16 17 3.6
2010 29,757,552 90.2 4 67 2.65 52 14 5 13.2
2011 30,075,050 90.3 11 77 3.28 71 7 10 7.8
2012 30,356,544 90.6 13 101 4.14 94 14 6 18.0
2013 30,604,240 88.7 15 114 4.75 94 25 10 11.9
2014 31,328,211 88.2 16 116 4.78 104 22 6 21.0
2015 31,977,800 92.0 10 121 4.45 101 24 6 20.8

*CIS, case isolates serotyped; IPD, invasive pneumococcal disease.
†Estimated cases/million = total 35Bs x 100/% CIS surveillance population/1,000,000.

Main Article

TOP