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Volume 23, Number 8—August 2017
Research

Characterization of Fitzroy River Virus and Serologic Evidence of Human and Animal Infection

Cheryl A. Johansen1Comments to Author , Simon H. Williams1, Lorna Melville, Jay Nicholson, Roy A. Hall, Helle Bielefeldt-Ohmann, Natalie A. Prow, Glenys R. Chidlow, Shani Wong, Rohini Sinha, David T. Williams, W. Ian Lipkin, and David W. Smith
Author affiliations: The University of Western Australia, Nedlands, Western Australia, Australia (C.A. Johansen, J. Nicholson, S. Wong, D.W. Smith); PathWest Laboratory Medicine Western Australia, Nedlands (C.A. Johansen, G.R. Chidlow, D.W. Smith); Columbia University, New York, New York, USA (S.H. Williams, R. Sinha, W.I. Lipkin); The Northern Territory Government, Darwin, Northern Territory, Australia (L.F. Melville); The University of Queensland, St. Lucia, Queensland, Australia (R.A. Hall, H. Bielefeldt-Ohmann, N.A. Prow); The University of Queensland, Gatton, Queensland, Australia (H. Bielefeldt-Ohmann); CSIRO Australian Animal Health Laboratory, Geelong, Victoria, Australia (D.T. Williams)

Main Article

Table 1

Monoclonal antibody binding pattern of FRV isolates from Western Australia*

Virus
 Monoclonal antibody†
4G2
 4G4
 6F7
 7C6
 8G2
 6A9
 3D11
 3B11
 3G1
 5D3
 7C3
FRV‡ + + - – – – – – – – –
SEPV + + + – – – – – – – –
YFV + + – – – – – – – – –
EHV + – + + + + + + + + +

*EHV, Edge Hill virus; FRV, Fitzroy River virus; SEPV, Sepik virus; YFV, yellow fever virus; +, positive (optical density of >0.2 and at least 2 times the mean of negative control wells); –, negative.
†Original descriptions of monoclonal antibody from (31) (4G2), (32) (4G4), (33) (6F7), and (34) (7C6, 8G2, 6A9, 3D11, 3B11, 3G1, 5D3, and 7C3).
‡Monoclonal antibody binding patterns of all FRV isolates were identical to those of the prototype isolate K73884.

Main Article

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1These authors contributed equally to this article.

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