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Volume 23, Number 8—August 2017
Research

Characterization of Fitzroy River Virus and Serologic Evidence of Human and Animal Infection

Cheryl A. Johansen1Comments to Author , Simon H. Williams1, Lorna Melville, Jay Nicholson, Roy A. Hall, Helle Bielefeldt-Ohmann, Natalie A. Prow, Glenys R. Chidlow, Shani Wong, Rohini Sinha, David T. Williams, W. Ian Lipkin, and David W. Smith
Author affiliations: The University of Western Australia, Nedlands, Western Australia, Australia (C.A. Johansen, J. Nicholson, S. Wong, D.W. Smith); PathWest Laboratory Medicine Western Australia, Nedlands (C.A. Johansen, G.R. Chidlow, D.W. Smith); Columbia University, New York, New York, USA (S.H. Williams, R. Sinha, W.I. Lipkin); The Northern Territory Government, Darwin, Northern Territory, Australia (L.F. Melville); The University of Queensland, St. Lucia, Queensland, Australia (R.A. Hall, H. Bielefeldt-Ohmann, N.A. Prow); The University of Queensland, Gatton, Queensland, Australia (H. Bielefeldt-Ohmann); CSIRO Australian Animal Health Laboratory, Geelong, Victoria, Australia (D.T. Williams)

Main Article

Table 5

Fitzroy River virus replication in 4 cell lines

Day
 Mean Fitzroy River virus titer*
C6/36
 Vero
 BSR
 DF-1
1 0a 0a 3.07 ± 0.06b 0a
2 4.68 ± 0.21a 3.78 ± 0.05b 5.13 ± 0.06c 3.81 ± 0.3ab
3 5.58 ± 0.05a 4.72 ± 0.02b 6.67 ± 0.08c 5.5 ± 0.08a
4 6.66 ± 0.09a 5.02 ± 0.07b 6.72 ± 0.05a 6.26 ± 0.15a
7 4.41 ± 0.14a 7.01 ± 0.01b 6.6 ± 0.21b 4.25 ± 0.23a

*Statistical significance of log transformed arithmetic means was determined with 2-way analysis of variance with correction for multiple comparisons and using the Tukey method for pairwise multiple comparisons (GraphPad Prism version 6.0; GraphPad Software Inc, San Diego, CA, USA). Means in the same row followed by the same superscript letter did not differ significantly (p>0.05). Results at day 0 were excluded because virus detected at this time point represented residual inoculum.

Main Article

1These authors contributed equally to this article.

Page created: July 17, 2017
Page updated: July 17, 2017
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