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Volume 23, Number 8—August 2017
Research

Characterization of Fitzroy River Virus and Serologic Evidence of Human and Animal Infection

Cheryl A. Johansen1Comments to Author , Simon H. Williams1, Lorna Melville, Jay Nicholson, Roy A. Hall, Helle Bielefeldt-Ohmann, Natalie A. Prow, Glenys R. Chidlow, Shani Wong, Rohini Sinha, David T. Williams, W. Ian Lipkin, and David W. Smith
Author affiliations: The University of Western Australia, Nedlands, Western Australia, Australia (C.A. Johansen, J. Nicholson, S. Wong, D.W. Smith); PathWest Laboratory Medicine Western Australia, Nedlands (C.A. Johansen, G.R. Chidlow, D.W. Smith); Columbia University, New York, New York, USA (S.H. Williams, R. Sinha, W.I. Lipkin); The Northern Territory Government, Darwin, Northern Territory, Australia (L.F. Melville); The University of Queensland, St. Lucia, Queensland, Australia (R.A. Hall, H. Bielefeldt-Ohmann, N.A. Prow); The University of Queensland, Gatton, Queensland, Australia (H. Bielefeldt-Ohmann); CSIRO Australian Animal Health Laboratory, Geelong, Victoria, Australia (D.T. Williams)

Main Article

Table 2

Comparison of genomic region lengths and similarities between members of the YFV group and FRV*

FRV
SEPV
WESSV
YFV
nt
aa
nt
aa
nt
aa
nt
aa
5′ UTR 117 NA 116 (94) NA 118 (92) NA 118 (52) NA
Capsid 348 116 348 (77) 116 (84) 348 (74) 116 (78) 363 (54) 121 (39)
Premembrane 267 89 267 (78) 89 (94) 267 (73) 89 (87) 267 (59) 89 (59)
Membrane 225 75 225 (80) 75 (96) 225 (74) 75 (87) 225 (58) 75 (47)
Envelope 1,470 490 1,470 (81) 490 (96) 1,470 (79) 490 (93) 1,479 (63) 493 (54)
NS1 1,059 353 1,059 (79) 353 (93) 1,059 (76) 353 (87) 1,056 (63) 352 (64)
NS2a 678 226 678 (78) 226 (88) 678 (77) 226 (85) 672 (54) 224 (40)
NS2b 390 130 390 (78) 130 (88) 390 (76) 130 (88) 390 (56) 130 (50)
NS3 1,869 623 1,869 (79) 623 (93) 1,869 (77) 623 (92) 1,869 (67) 623 (71)
NS4a 378 126 378 (75)) 126 (87) 378 (75) 126 (92) 378 (61) 126 (57)
2k 69 23 69 (71) 23 (70) 69 (74) 23 (91) 69 (61) 23 (57)
NS4b 744 248 744 (79) 248 (94) 744 (77) 248 (91) 750 (66) 250 (64)
NS5 2,721 906 2,721 (78) 906 (88) 2,721 (76) 906 (89) 2,718 (66) 905 (68)
3′ UTR 472 NA 459 (86) NA 478 (84) NA 508 (65) NA
Polyprotein 10,218 3,405 10,218 (79) 3,405 (91) 10,218 (77) 3,405 (89) 10,236 (63) 3,411 (61
Full genome 10,807 NA 10,793 (79) NA 10,814 (77) NA 10,862 (62) NA

*Values are sequence length (% identity with FRV). FRV, Fitzroy River virus (GenBank accession no. KM 361634); NS, nonstructural; SEPV, Sepik virus (GenBank accession no. NC008719); UTR, untranslated region; WESSV, Wesselsbron virus (accession no. JN226796); YFV, yellow fever virus (X03700); NA, not applicable.

Main Article

1These authors contributed equally to this article.

Page created: July 17, 2017
Page updated: July 17, 2017
Page reviewed: July 17, 2017
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