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Volume 23, Number 8—August 2017
Research

Characterization of Fitzroy River Virus and Serologic Evidence of Human and Animal Infection

Cheryl A. Johansen1Comments to Author , Simon H. Williams1, Lorna Melville, Jay Nicholson, Roy A. Hall, Helle Bielefeldt-Ohmann, Natalie A. Prow, Glenys R. Chidlow, Shani Wong, Rohini Sinha, David T. Williams, W. Ian Lipkin, and David W. Smith
Author affiliations: The University of Western Australia, Nedlands, Western Australia, Australia (C.A. Johansen, J. Nicholson, S. Wong, D.W. Smith); PathWest Laboratory Medicine Western Australia, Nedlands (C.A. Johansen, G.R. Chidlow, D.W. Smith); Columbia University, New York, New York, USA (S.H. Williams, R. Sinha, W.I. Lipkin); The Northern Territory Government, Darwin, Northern Territory, Australia (L.F. Melville); The University of Queensland, St. Lucia, Queensland, Australia (R.A. Hall, H. Bielefeldt-Ohmann, N.A. Prow); The University of Queensland, Gatton, Queensland, Australia (H. Bielefeldt-Ohmann); CSIRO Australian Animal Health Laboratory, Geelong, Victoria, Australia (D.T. Williams)

Main Article

Table 6

Serologic test results for 9 serum samples from humans from northern Western Australia, which contained FRV neutralizing antibodies at initial testing*

Sample
 ELISA, % block
 FRV initial neutralization titer
 Cross-neutralization titers Infecting virus
FRV
 MVEV
 KUNV
 ALFV
 KOKV
 STRV
 EHV
2014–1 79 10 <10 <10 <10 <10 <10 <10 <10 UD
2014–2 87 20 <10 10 10 <10 10 10 40 EHV
2014–3 86 40 <10 <10 <10 <10 <10 20 80 EHV
2014–4 84 160 40 <10 10 <10 <10 10 <10 FRV
2015–1 90 80 <10 <10 160 <10 <10 <10 <10 KUNV
2015–2 92 20 <10 <10 80 <10 <10 <10 <10 KUNV
2015–3 98 40 80 <10 10 <10 <10 <10 <10 FRV
2015–4 95 80 80 10 20 <10 10 10 20 FRV
2015–5 98 10 <10 <10 10 <10 <10 <10 <10 UD

*ALFV, Alfuy virus (K74157); EHV, Edge Hill virus (K74003); FRV, Fitzroy River virus (K73884); KOKV, Kokobera virus (K69949); KUNV, West Nile (Kunjin) virus (K81136); MVEV, Murray Valley encephalitis virus (K68150); STRV, Stratford virus (C338); UD, undetermined.

Main Article

1These authors contributed equally to this article.

Page created: July 17, 2017
Page updated: July 17, 2017
Page reviewed: July 17, 2017
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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