Multiplex PCR−Based Next-Generation Sequencing and Global Diversity of Seoul Virus in Humans and Rats
Won-Keun Kim
1, Jin Sun No
1, Seung-Ho Lee, Dong Hyun Song, Daesang Lee, Jeong-Ah Kim, Se Hun Gu, Sunhye Park, Seong Tae Jeong, Heung-Chul Kim, Terry A. Klein, Michael R. Wiley, Gustavo Palacios, and Jin-Won Song
Author affiliations: Korea University, Seoul, South Korea (W.-K. Kim, J.S. No, S.-H. Lee, J.-A. Kim, J.-W. Song); Agency for Defense Development, Daejeon, South Korea (D.H. Song, D. Lee, S.H. Gu, S. Park, S.T. Jeong); 65th Medical Brigade/Medical Department Activity−Korea, Seoul (H.-C. Kim, T.A. Klein); US Army Medical Research Institute of Infectious Disease, Fort Detrick, Maryland, USA (M.R. Wiley, G. Palacios)
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Figure 1
Figure 1. Measurement of SEOV RNA loads in different tissues of Rattus norvegicus rats, South Korea, 2000–2016. Ct values were determined for SEOV small segment RNA in lung, liver, kidney, and spleen tissues obtained from 5 rats positive for SEOV IgG and SEOV RNA. Solid horizontal line indicates assay cutoff value. Ct, cycle threshold; S, small; SEOV, Seoul virus.
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